Owing to striking features of numerous multinucleated cells and bone destruction, giant cell tumor (GCT) of bone, often called as osteoclastoma, has drawn major attractions from orthopaedic surgeons, pathologists, and radiologists. The name GCT or osteoclastoma gives a false impression of a tumor comprising of proliferating osteoclasts or osteoclast precursors. The underlying mechanisms for exc...

INTRODUCTION: Granular Cell tumor(GCT) is an uncommon soft tissue tumor with an incidence of 0.017 – 0.029 % in general surgical specimen 1. They usually occur as solitary tumors, but are multiple in about 10% of the cases 2. Though the most common site of involvement is the tongue 3, it is also found in other sites. Granular cell tumor was originally described in 1926 as granular cell myoblato...

We report a case of Giant Cell Tumor (GCT) arising from anterior are of first rib along with literature review which was treated with excision of rib through its normal margin along with tumor mass. GCT of rib is rare and if found mostly arises from the posterior aspect. However, GCT should be considered as differential diagnosis when bony mass is present in the anterior are of rib. It poses su...

Germinomas and embryonal carcinomas are central nervous system (CNS) germ cell tumors (GCT) that may overexpress the proto-oncogene c-KIT, a receptor tyrosine kinase, of which dasatinib is a potent inhibitor. This retrospective review presents the feasibility and tolerability of dasatinib administration in select patients with CNS germinoma. Between November 2008 and April 2010, six patients wi...

Granular cell tumor (GCT) is an uncommon, usually benign neoplasm; however, a malignant potential has been described. Malignant GCT is an extremely rare neoplasm showing rapid growth and invasion into adjacent muscles, lymph nodes, or vessels, or even distant metastasis. We recently experienced a case of a histologically benign or atypical but clinically malignant GCT, with invasion of the lymp...

BACKGROUND Esophageal granular cell tumor (GCT) is a rare benign tumor with malignant potential. With wide application of endoscopic techniques, the esophageal GCT discovery rate and treatment strategy has changed. This study was to preliminarily evaluate outcomes of endoscopic diagnosis and treatment for esophageal GCT. METHODS Fourteen patients (eight men, six women; median age, 48.5 years)...

In this paper, we propose a graph correspondence transfer (GCT) approach for person re-identification. Unlike existing methods, the GCT model formulates person re-identification as an off-line graph matching and on-line correspondence transferring problem. In specific, during training, the GCT model aims to learn off-line a set of correspondence templates from positive training pairs with vario...

Background. We report on 19 cases of giant cell tumor of bone (GCT) affecting the spine or sacrum and evaluate the outcome of different treatment modalities. Methods. Nineteen patients with GCT of the spine (n = 6) or sacrum (n = 13) have been included in this study. The mean followup was 51.6 months. Ten sacral GCT were treated by intralesional procedures of which 4 also received embolization,...

OBJECTIVE The treatment of giant cell tumor (GCT) is mainly performed surgically. However, GCT in spine seems difficult to treat because of the limited surgical accessibility and proximity. In this report, we analyzed the outcome of GCT treatment in spine. METHODS Between 2000 and 2012, 19 patients received treatment for GCT in spine. Median age at their first diagnosis was 31 years, 10 patie...

Geometric complexity theory (GCT) is an approach to the P vs. NP and related problems through algebraic geometry and representation theory. This article gives a high-level exposition of the basic plan of GCT based on the principle, called the flip, without assuming any background in algebraic geometry or representation theory.