A novel bioartificial dermal regeneration template has been developed using platelet-rich plasma and acellular animal skin collagen sponge for the treatment of larger area and full thickness skin wounds. This platelet-rich plasma-collagen sponge keeps native skin structure and contains huge amounts of growth factors. The effect of this bioartificial dermal regeneration template was tested in vi...

BACKGROUND Pin site infection is a common problem in external fixation. Plain gauze wetted with normal saline is commonly used for a pin site dressing owing to the simplicity and low cost. Evidence to support adding an antimicrobial agent in the dressing material is lacking. QUESTIONS/PURPOSES We compared the rate of pin tract infection using plain gauze and gauze impregnated with polyhexamet...

Although gauze packing and planned reoperation has been documented for the treatment of liver trauma, it has not been described for the management of the ruptured spleen. We document a single case of a grade I splenic injury, which occurred during an emergency subtotal colectomy for a massive lower gastrointestinal bleed. The options of suturing and packing with absorbable mesh failed in the pr...

Introduction: Gum Tragacanth (GT) obtained from Astragalus gossypinus is one of the most widely used natural gums which has found applications in many areas because of its attractive features such as biodegradability, nontoxic nature, natural availability, moisture absorption and creating a network of Hydrocolloid. It also has properties like maintenance and delivery of drugs, higher resistance...

Encrusting and excavating Caribbean sponges Cliona aprica, C. caribbaea and C. tenuis (Hadromerida: Clionaidae) aggressively undermine and displace live coral tissue. To establish modes and rates of lateral advance into neighboring organisms, 171 sponge individuals were studied for 13 mo. Sponge advancement into live coral, via excavation underneath boundary polyps, occurred only when the 2 con...

The chemistry of the burrowing sponge Aka coralliphagum was investigated to identify chemically labile secondary metabolites. The HPLC-MS analysis of the two growth forms typica and incrustans revealed different metabolites. The previously unknown sulfated compounds siphonodictyals B1 to B3 (6-8), corallidictyals C (9) and D (10), and siphonodictyal G (11) were isolated, and their structures we...