Many problems of operations research or decision science involve continuous probability distributions, whose handling may be sometimes unmanageable; in order to tackle this issue, different forms approximation methods can used. When constructing a k-point discrete random variable, moment matching, i.e., matching as many moments possible the original distribution, is most popular technique. This...

In this study we demonstrate that the demosponge Suberites domuncula harbors a Mn(II)-oxidizing bacterium, a Bacillus strain, termed BAC-SubDo-03. Our studies showed that Mn(II) stimulates bacterial growth and induces sporulation. Moreover, we show that these bacteria immobilize manganese on their cell surface. Comparison of the 16S rDNA sequence allowed the grouping of BAC-SubDo-03 to the Mn-p...

We discuss in this paper the strong convergence for weighted sums of negatively orthant dependent (NOD) random variables by generalized Gaussian techniques. As a corollary, a Cesaro law of large numbers of i.i.d. random variables is extended in NOD setting by generalized Gaussian techniques.

We recently identified the protein phosphatase-1 - targeting compound, 1E7-03 which inhibited HIV-1 in vitro. Here, we investigated the effect of 1E7-03 on HIV-1 infection in vivo by analyzing its metabolic stability and antiviral activity of 1E7-03 and its metabolites in HIV-1 infected NSG-humanized mice. 1E7-03 was degraded in serum and formed two major degradation products, DP1 and DP3, whic...

BACKGROUND Data on allele frequencies (AFs) and haplotype frequencies (HFs) of HLA-C and -DQB1 are limited in Koreans. We investigated AFs and HFs of HLA-A, -B, -C, -DRB1, and -DQB1 in Koreans by high-resolution sequence-based typing (SBT). METHODS Hematopoietic stem cells were obtained from 613 healthy, unrelated donors to analyze HLA-A, -B, -C, -DRB1, and -DQB1 genotypes by using AlleleSEQR...

Because of the potential of a new anti-staphylococcal lead compound SK-03-92 as a topical antibiotic, a patch, or an orally active drug, we sought to determine its safety profile and oral bioavailability. SK-03-92 had a high IC50 (125 μg/ml) in vitro against several mammalian cell lines, and mice injected intraperiteonally at the highest dose did not exhibit gross toxicity (e.g. altered gait, u...

laser forming is a modern process which is mainly used for forming metals. different lasers are used in this regard that includes nd: yag and co2. in this study, forming bi-layer sheets of aluminum/ceramic by laser was investigated. furthermore, effect of uniform and gaussian heat flux distribution in different power, velocity, and beam diameters on bending angle was studied. fem simulation ind...

Abstract: Stochastic models such as mixture models, graphical models, Markov random fields and hidden Markov models have key role in probabilistic data analysis. In this paper, we used Gaussian mixture model to the pixels of an image. The parameters of the model were estimated by EM-algorithm.   In addition pixel labeling corresponded to each pixel of true image was made by Bayes rule. In fact,...