The gastrointestinal motility changes that occur as a function of age are reviewed herein. Careful attention must be given in any review of aging phenomena to exclude, or at least be cognizant of, the many comorbid conditions that can alter physiological functioning in older adults. The dramatic increase in life expectancy over the past 10-15 years demands that clinicians be aware of the variou...

Gastrointestinal diseases, including motility and obstructive disorders, are common in both human and veterinary medicine. Such disorders tend to be clinically important problems in both disciplines, with extensive impact on veterinary practice as well as having human public health and economic implications. Considerable time is lost from work due to gut disorders. Motor disorders of the gastro...

Japanese macaques bred indoor for laboratory use often show chronic anorexia and intermittent vomiting. In some of our macaques gastric air was observed on physical examination, and we suspected abnormality of gastric motility. We therefore performed contrast radiographic examinations of the gastrointestinal tract without anesthesia of 8 macaques with gastrointestinal symptoms and 9 asymptomati...

Objective(s) Achillea genius is widely used in traditional medicine for gastrointestinal disorders. The aim of this study was to investigate the effects of aqueous-ethanol extract of Achillea wilhelmsii on rat’s gastric motility in basal and vagal stimulated conditions. Materials and Methods Twenty four Wistar rats were randomly divided into two groups: control and test. The extract was prep...

Multiple approaches have been used to record and evaluate gastrointestinal motility including: recording changes in muscle tension, intraluminal pressure, and membrane potential. All of these approaches depend on measurement of activity at one or multiple locations along the gut simultaneously which are then interpreted to provide a sense of overall motility patterns. Recently, the development ...

Background Recently with the improvement of people’s living standards, eating fine, irregular life, lack of exercise and increased mental stress, the incidence of constipation is increasing. Gastrointestinal (GI) tract’s pressure information can reflect the dynamic disorder of gastrointestinal physiological and pathological changes, which is important in early diagnosis and treatment of constip...

Gastrointestinal dysfunction is common in Parkinson's disease. Fiber therapy could be used to reduce the symptoms of gastrointestinal motility disorders. In a previous study, we showed that slowed gastrointestinal motility modified levodopa pharmacokinetics: area under the plasma concentration-time curve (AUC) and maximum plasma concentration (C(max)) decreased and the elimination was delayed. ...

Abstract Introduction Due to the growing interest in use of cannabinoids supportive therapies, they are increasingly used together with anti-inflammatory drugs. Cannabinoids inhibit gastrointestinal motility, while steroidal and nonsteroidal drugs influence motility other ways. The aim research was study interactions between cannabidiol (CBD) these two classes context motility. Dexamethasone (D...