Although the GI tract is the most common site of low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT),1,2 duodenal MALT lymphoma is rare.3-10 The eradication of Helicobacter pylori is now considered the treatment of choice for gastric MALT lymphoma,11-14 yet therapeutic strategies for duodenal MALT lymphoma are still in dispute.3-10 This is a report of 2 cases of duodenal MALT ...

RATIONALE Burkitt lymphoma (BL) is an endemic tumor in Africa but rare sporadic cases are diagnosed in Europe. PATIENT CONCERNS A 60-year-old woman was hospitalized with fulminant hematemesis and a history of recurring melena. DIAGNOSES The upper gastrointestinal endoscopy revealed a tumor of the antrum. INTERVENTIONS Emergency gastrectomy was performed. OUTCOMES Gross findings revealed...

The concept of mucosa-associated lymphoid tissue (MALT) lymphomas was introduced by Isaacson and Wright [Cancer 1983; 52:1410-1416] in 1983. After more than 20 years of clinical research MALT lymphomas are now recognized as a distinct subtype of non-Hodgkin's lymphoma (NHL) with unique pathogenic, histological, and clinical features. Although this subtype of NHL occurs frequently, optimal manag...

The diagnosis of gastric MALT lymphoma is frequently difficult for the general histopathologist. During recent years there have been relevant changes in the therapeutic approach to gastric MALT lymphoma and our knowledge about its pathogenesis has greatly improved. The management of this disease actually requires a close cooperation between the histopathologist and the clinicians. The histology...

Follicular lymphoma (FL) of the gastrointestinal tract, particularly duodenal follicular lymphoma (DFL), is a rare variant of FL with indolent clinical behavior, and this disease is included in the 2008 World Health Organization classification system. In contrast to nodal follicular lymphoma (NFL), DFL occurs most frequently in the second part of the duodenum, lacks follicular dendritic cell me...

A median 80 months follow-up with updated time to progression (TTP) and survival data is presented from a multicenter phase II trial using 2-Chlorodeoxyadenosine (2-CdA) in the treatment of extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue type (MALT lymphoma) [1]. With the exception of Helicobacter pylori (HP) eradication therapy in localized gastric disease no ...

Familial lymphoma is uncommon and is usually associated with various forms of hereditary immunodeficiencies. Primary gastric lymphomas that occurred in three adults from the same family, who had no overt immunodeficiency or cancer of non-lymphomatous origin, are reported. Two sisters presented with a low grade lymphoma of the mucosa associated lymphoid tissue type. Their father presented with a...

BACKGROUND Primary Hodgkin's disease of the stomach is an extremely rare entity. Nearly all cases of primary gastric lymphoma are of the non-Hodgkin's variety. Diagnoses in such cases are difficult due to considerable histological similarities between the 2 disease entities. CASE PRESENTATION We report the case of a 77 year old lady with a 1 year history of weight loss and poor appetite. Phys...

Recent reports have suggested an association between Helicobacter pylori infection and both gastric mucosa associated lymphoid tissue (MALT) lymphoma and thrombocytopenic purpura. Although treatments eradicating H pylori lead to regression of these diseases in some cases, the exact mechanisms are still controversial. This case report describes a patient with thrombocytopenic purpura accompanied...

This study assessed the presentation, treatment, and prognosis of primary gastric lymphoma in general hospital practice and its relation to infection with Helicobacter pylori. The number of patients that would on the current recommendations have been suitable for H pylori eradication therapy was also examined. All lymphomas were graded according to a standard classification of gut lymphoma into...