CodY is a branched-chain amino acid (BCAA) and GTP sensor and a global regulator of transcription in low G + C Gram-positive bacteria. It controls the expression of over 100 genes and operons, principally by repressing during growth genes whose products are required for adaptations to nutrient limitation. However, the mechanism by which BCAA binding regulates transcriptional changes is not clea...

PURPOSE To analyze the clinical characteristics of nontuberculous mycobacterial (NTM) ocular infections and the species-specific in vitro antimicrobial susceptibility. MATERIAL AND METHODS In 2000 to 2011 at the National Taiwan University Hospital, multilocus sequencing of rpoB, hsp65 and secA was used to identify NTM isolates from ocular infections. The clinical presentation and treatment ou...

In their study of rehabilitation services in England, Killaspy and co-authors conclude that 'Quality of care is linked to better clinical outcomes in people with complex and longer-term mental health problems'. 1 We are not persuaded that this conclusion is justified by the results reported. The study investigated the relationship between measures of quality and clinical outcomes across a numbe...

Söderberg, Per & Tungström, Stefan (2007). Outcome in psychiatric outpatient services: Reliability, validity and outcome based on routine assessments with the GAF scale. Doctoral dissertation from the Department of Psychology, Umeå University, S-901 87 UMEÅ, Sweden: ISBN 91-7264-240-8; ISBN 978-91-7264-240-9 The general aim of the studies presented in this thesis is to investigate the possibili...

The GafD lectin of the G (F17) fimbriae of diarrhea-associated Escherichia coli was overexpressed and purified from the periplasm of E. coli by affinity chromatography on GlcNAc-agarose. The predicted mature GafD peptide comprises 321 amino acids, but the predominant form of GafD recovered from the periplasm was 19,092 Da in size and corresponded to the 178 N-terminal amino acid residues, as ju...

BACKGROUND No controlled trials have evaluated the long term efficacy of exercise activity to improve the treatment of patients with Major Depressive Disorders. The aim of the present study was to confirm the efficacy of the adjunctive physical activity in the treatment of major depressive disorders, with a long term follow up (8 months). METHODS Trial with randomized naturalistic control. Pa...

BACKGROUND Patient satisfaction is an important, but controversial part of health service evaluation. This study dealt with how acknowledgement of illness and treatment needs effected the distribution of positive, neutral and negative evaluations in a group of first time admitted patients to a psychiatric hospital. METHOD The participants filled out a standardized user satisfaction form befor...