While the hippocampal memory system has been relatively conserved across mammals, the cerebral cortex has undergone massive expansion. A central question in brain evolution is how cortical development affected the nature of cortical inputs to the hippocampus. To address this question, we compared cortico-hippocampal connectivity using intrinsic functional connectivity MRI (fcMRI) in awake mice ...

Study of neural correlates of ADHD could potentially help us to develop an automated diagnosis system. In 2011, a rich and heterogeneous neuroimaging dataset was provided by the ADHD-200 consortium to be used for this purpose. Considering the fact that the brain functional connectome in ADHD subjects is altered compared to healthy controls; we hypothesized that local and global parameters of fu...

The algebraic connectivity of a graph G is the second smallest eigenvalue of its Laplacian matrix. Let Bn be the set of all bicyclic graphs of order n. In this paper, we determine the last four bicyclic graphs (according to their smallest algebraic connectivities) among all graphs in Bn when n > 13. This result, together with our previous results on trees and unicyclic graphs, can be used to fu...

Resting state functional connectivity MRI (rs-fcMRI) may provide a powerful and noninvasive "bridge" for comparing brain function between patients and experimental animal models; however, the relationship between human and macaque rs-fcMRI remains poorly understood. Here, using a novel surface deformation process for species comparisons in the same anatomical space (Van Essen, 2004, 2005), we f...

BACKGROUND Awake craniotomy is currently the gold standard for aggressive tumor resections in eloquent cortex. However, a significant subset of patients is unable to tolerate this procedure, particularly the very young or old or those with psychiatric comorbidities, cardiopulmonary comorbidities, or obesity, among other conditions. In these cases, typical alternative procedures include biopsy a...

Recently, there has been an increasing emphasis on applications of pattern recognition and neuroimaging techniques in the effective and accurate diagnosis of psychiatric or neurological disorders. In the present study, we investigated the whole-brain resting-state functional connectivity patterns of Parkinson's disease (PD), which are expected to provide additional information for the clinical ...

Recent resting-state functional connectivity magnetic resonance imaging studies have shown significant group differences in several regions and networks between patients with major depressive disorder and healthy controls. The objective of the present study was to investigate the whole-brain resting-state functional connectivity patterns of depressed patients, which can be used to test the feas...