the aim of this study was to evaluate an enzyme - linked immunosorbent assay (elisa) for the detection of anti - helicobacter pylori (h. pylori) specific igg antibodies in specimens of oral fluid. all subjects over the age 18 years undergoing endoscopy for any reason were asked to participate in the study. two groups of 44 patients in each were selected as hp+ and hp-. at the same time, 5 milli...

lipopolysaccharide (lps) is an important structural component of the outer cell membrane complex of gram-negative microorganisms. its causative role in gram-negative bacteria-induced diseases and broad applications in different kinds of cell stimulation experiments provided a conceptual basis for studies directed at the isolation, purification, and detailed chemical characterization of lps. the...

Protein hydrolysates and peptides can show biological activities, pulsed ultrasound improves bioactivities. Among matrices from which protein be obtain, chickpea is an excellent source. The objective of this research was to evaluate the effect on globulin concentrate obtain hydrolysate (HGb) peptide fractions their bioactivity. Antioxidant activity by ABTS (2,2′-Azino-bis(3-ethylbenzothiazoline...

The neuronal protein α-synuclein (α-syn) is one of the main constituents intracellular amyloid aggregations found in post-mortem brains Parkinson’s disease (PD) patients. Recently, we screened MEOH extracts obtained from 300 sub-tropical marine invertebrates for α-syn binding activity using affinity MS and this resulted extract Verongida sponge Aplysinella sp. 1194, (QM G339263) displaying mole...

BACKGROUND The histamine H3 receptor is an attractive G protein-coupled receptor drug target that regulates neurotransmission in the central nervous system and plays a crucial role in cognitive and homeostatic functions. This receptor exhibits molecular, pharmacological, and functional heterogeneity that affects the preclinical development of effective antagonists. The range of assay technologi...

This study evaluated the functional components of hazelnut waste products (cuticles and shells) for potential use in circular economy. HPLC-HRMS ABTS assay were used to determine molecules with properties antioxidant capacity, respectively. The capacity cuticles shells was tested using two different methods extraction (EtOH 50/50 acetone 40/70) by radical cation decolorization assay. growth inh...

OBJECTIVES To explore the correlation between expression patterns and functions of miR-383 and LDHA in hepatocellular cancer (HCC). MATERIALS AND METHODS We detected the expression of miR-383 and LDHA in 30 HCC tissues and their matched adjacent normal tissues using qRT-PCR. Then we performed MTT assay, foci formation assay, transwell migration assay, glucose uptake assay and lactate producti...

0

The present research signifies the anti-obesity potential of Bougainvillea spectabilis Willd. and its techno-functional properties. is a medicinal plant that belongs to Nyctaginaceae family. Studies have reported various bioactive compounds such as flavonoids, phenols, alkaloids, saponins, tannins, etc., in Willd., responsible for biological properties antibacterial, antidiabetic, antioxidant, ...