background: evidence has shown a link between allergic disease and inflammatory bowel diseases (ibds). we investigated food allergy in iranian pediatric ibd patients. materials and methods: a cross-sectional study was conducted on a consecutive sample of children with newly  diagnosed ibd referring to mofid children’s university hospital in tehran (iran) between november 2013 and march 2015.dat...

beta-lactams are a group of antibiotics with a broad spectrum of both gram-negative and gram-positive coverage. the goal of this study is to evaluate the results from studies regarding ig-e mediated hypersensitivity to penicillin and cross-reactivity with other beta-lactams. review was conducted of both retrospective and prospective studies by searching in pubmed and medline for the original an...

the hyperimmunoglobulin e  syndrome is a rare complex primary immunodeficiency characterized by high serum ige levels, eczema, and recurrent infections. we present a case of 2-years-old girl with eczema and repeated bacterial skin and lung infections since the period of infancy. the patient also had eosinophilia, high serum levels of ige, and cows-milk hypersensitivity. we describe the case, in...

background: allergens are mostly composed of glycoprotein structures. it is believed that glycan-specific antibodies may lead to false-positive reactions in immunoassays. in this study we investigated the glycosylation state of grape allergens as well as the presence of antibodies to cross-reactive carbohydrate determinants (anti-ccds) in sera from grape-sensitive individuals. methods: grape ex...

Individual approaches to the diagnosis and management of penicillin allergy are practiced    by clinicians.   This cross-sectional survey of physicians was aimed at exploring their ways of dealing with diagnosis and management of penicillin G allergy.   Of the 235 respondents, 63% believed patients’ self-reported history of penicillin allergy and avoided using penic...

The Council acknowledges specific comments from: The American Academy of Allergy, Asthma and Immunology (AAAAI) (Amal H Assa'ad); The American College of Allergy, Asthma and Immunology (ACAAI) (Mark Dykewicz, D. Betty Lew, Bryan L. Martin); The Argentine Association of Allergy and Immunology (Ledit RF Ardusso); The Argentine Society of Allergy and Immunopathology (Estrella Asayag); The Australa...

Although food allergy is a major public health problem, currently there is no effective and safe treatment except to avoid the foods .But the need for new options is critical now as the number of children diagnosed with food allergies rises. Avoiding the offending allergen in the diet is the primary treatment of food allergy. Once a food to which the patient is sensitive has been identified, th...

nasal polyposis is an inflammatory condition of unknown etiology that involves nasal and sinus mucous membrane. these polyps can impair a person’s quality of life by nasal obstruction, recurrent sinusitis, persistent postnasal drainage, hyposmia, anosmia, changes in sense of taste and even bony destruction. it has been shown that chronic inflammation causes a reactive hyperplasia of the intrana...