The scabrous (sca) gene encodes a secreted dimeric glycoprotein with putative coiled-coil domains N-terminally and a C-terminal region related to the blood clot protein fibrinogen. Homozygous sca mutants have extra bristle organs and rough eyes. We describe a GAL4-based expression system for testing rescue of the sca mutant phenotype by altered SCA proteins and for misexpression. We find that d...

In this paper we present and describe a large quarterly frequency, macroeconomic database. The data provided are closely modeled to that used in Stock Watson (2012a). As our previous work on FRED-MD, goal is simply provide publicly available source of “big data” updated real time using the FRED We show factors extracted from set exhibit similar behavior those original set. dominant shown be ins...

If a person knows that Fred ate a pizza, then they can answer the following questions: Who ate a pizza?, What did Fred eat?, What did Fred do to the pizza? and even Who ate what? This and related properties we are terming accessibility properties for the relational fact that Fred ate a pizza. Accessibility in this sense is a significant property of human cognitive performance. Among neural netw...

There is a link between Oliver Wendell Holmes’ poem “The One-Hoss Shay” (1) and every patient with diabetes who has ever received a kidney or pancreas transplant. Yet, most of the 4,128 diabetes patients in the U.S. who received renal transplants in 2011 (2) and the 1,051 diabetes patients who received a pancreas transplant in 2011 (3) do not know how Dr. Frederick C. Goetz (1922–2012) used thi...