Generalized hyperpigmentation (GHPT) of the skin may occur as a primary defect of pigmentation or in combination with other variable manifestations. It is visible in a number of diseases such as Addison’s disease (AD), haemochromatosis, porphyria cutanea tarda, scleroderma and neurofibromatosis, but it can also be associated with malignancy and the use of chemotherapeutics or it can be related ...

The skin penetration and safety of nanometric zinc oxide and titanium dioxide incorporated in a cosmeceutical cream, specifically designed to retard skin actinic damage in tropical Oculocutaneous albinism was investigated ex-vivo through simulated actinically damaged porcine skin. Franz diffusion cells were used in an experiment modeled in line with related work done by Diembeck et al (1999); t...

Since ancient times, a face with fair skin is considered as a sign of beauty and the demand for young, healthy, bright and fair skin has created a whitening cosmetics market. The color of human skin and hair established through a number of factors. Melanogenesis i.e. the biosynthesis of melanin is the major factor. It is a multistage process involving melanin synthesis in special organelles cal...

In the modern world, a reliable personal identification infrastructure is required to control the access in order to secure areas or materials. Conventional methods of recognizing the identity of a person by using passwords or cards are not altogether reliable, because they can be forgotten, stolen, disclosable, or transferable (Zhang, 2000). Biometric technology, which is based on physical and...

Latanoprost, a 17-phenyl–substi-tuted analog of PGF 2 ␣, has been shown to effectively lower intraocu-lar pressure in clinical trials and darken the irides in both subhuman primates and humans. 1 The reported time of onset of the change in iris color has been noted to be as early as 3 months. To our knowledge , this case represents the earliest reported change in iris color following the initia...

CMAJ © 2010 Canadian Medical Association or its licensors 1 A10-year-old boy presented with a three-year history of recurrent lesions on photoexposed areas that worsened each summer. The boy had no family history of photosensitivity. Some vesicles and tiny depressed scars resembling chickenpox scars were present on his arms, face and ears. He had freckles on his face and a deep ulcer covered wi...

A case of cystic foreign body giant cell granuloma is presented. The patient, nineteen years of age, known case of Xeroderma Pigmentosum, presented to the maxillofacial unite, Basrah General Hospital, Iraq, with slowly enlarging cervical cystic mass. Examination revealed cystic swelling in the mid-left side of the neck of six months duration. The mass was not tender and was immobile. Aspiration...

BACKGROUND Photodamage describes skin changes such as fine and coarse wrinkles, roughness, freckles and pigmentation changes that occur as a result of prolonged exposure to the sun. Many treatments are available to reverse the damage, but it is unclear which work and at what cost in terms of unwanted side effects. OBJECTIVES To assess the effects of topically applied treatments, tablet treatm...

The recently published paper by Rankin et al. [1] ‘‘Iris recognition failure over time: The effects of texture’’ is paradoxical because in fact no changes over time were demonstrated, either in the iris patterns or in the system performance. The authors measured iris recognition performance using ‘‘local and non-local dipole and tripole’’ methods of iris feature extraction proposed by Sun et al...

A population-based study to investigate the epidemiological, genetic and clinical features of neurofibromatoses (NF) in Northern Finland was carried out between 1989-1996. The area concerned was that served by Oulu University Hospital, with a total population of 733 037. A total of 197 patients with neurofibromatosis type 1 (NF1), five with neurofibromatosis type 2 (NF2) and eight with segmenta...