The bacterial Lux system is used as a gene expression reporter. It is fast, sensitive and non-destructive, enabling high frequency measurements. Originally developed for bacterial cells, it has also been adapted for eukaryotic cells, and can be used for whole cell biosensors, or in real time with live animals without the need for euthanasia. However, correct interpretation of bioluminescent dat...

INTRODUCTION Older men are at increased risk for prostate cancer. As seniors turn to the Internet for cancer information, it is important that the resources they locate about lifestyle behaviors and screening are culturally appropriate and easy to understand. This study was a comprehensive analysis of prostate cancer risk as portrayed on the Internet with assessment of content readability and c...

BACKGROUND The Internet has become the most widely-used source for patients seeking information more about their health and many sites geared towards this audience have gained widespread use in recent years. Additionally, many healthcare institutions publish their own patient-education web sites with information regarding common conditions. Little is known about how these resources impact patie...

For effective water-based thermal management of high heat generating CPU chip, a series numerical simulation has been conducted to study the effects flux, fin height and flow rate on convective performance plate-fin microchannel sinks. The characteristics transfer resistance have quantificationally discussed JF factor is employed evaluate comprehensive efficiency sink. Results show that ...

Key message The TreeTrace_Douglas database includes images and measurements at several stages of the processing Douglas fir logs, from sawmill logyard to machine grading destructive testing boards, is suitable for research on quality assessment traceability. A total 52 long 156 short 208 wood discs, 346 boards were analyzed. image data RGB log ends board ends, CT slices strips, a set (RGB, lase...

O presente artigo tem como objetivo analisar o índice de Sharpe sob Endividamento das empresas, assim verificando a hipótese que uma empresa com maior indicador possui também um risco e, portanto menor Sharpe. Na metodologia, os dados foram obtidos através dos Formulários Referência (FRE) da BM&FBovespa (B3), empresas carteira Teórica do Ibovespa, entre período 1996 2016. Para verificar rel...

Aiming at the problems that tomatoes are fragile and traditional end-effector design is not suitable for tomato picking, a combination of bionic principle FRE structure finger was proposed. Based on physical properties tomatoes, flexible underactuated picking sorting designed. The optimal structural parameters fingers were determined by finite element analysis, grasping experiment carried out. ...

Pokemon 1 is a proto-oncogenic transcriptional regulator that contains a POZ domain at the N-terminus and four Kruppel-like zinc fingers at the C-terminus. Pokemon 1 plays an important role in adipogenesis, osteogenesis, oncogenesis, and transcription of NF-kB responsive genes. Recent reports have shown that biological activities of transcription factors are regulated by sumolylation. We invest...

Muscle-specific RING finger-1 (MuRF-1), a ubiquitin ligase and key regulator of proteasome-dependent protein degradation, is highly expressed during skeletal muscle atrophy. The transcription factor forkhead box O3 (FoxO3) induces MuRF-1 expression, but the direct role of other major atrophy-related transcription factors, such as SMAD3, is largely unknown. The goal of this study was to determin...