objective(s):  denaturing high performance liquid chromatography (dhplc) is a high throughput approach for screening dna sequence variations. to assess oven calibration, cartridge performance, buffer composition and stability, the wave low and high range mutation standards are employed to ensure reproducibility and accuracy of the chromatographic analysis. the purpose of this study was to provi...

An insight into the structural features of human Waldenstr6m IgM proteins which are responsible for their capacity to bind and activate the first component of complement (C) has been obtained . The basic approach has involved enzymatic and chemical fragmentation of the IgM molecule followed by examination of the resulting fragments for C-fixing activity . A 6,800 mol wt fragment obtained from t...