نتایج جستجو برای: foxa1

تعداد نتایج: 520  

Journal: :Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 2019

2016
Michael J.G. Milevskiy Fares Al-Ejeh Jodi M. Saunus Korinne S. Northwood Peter J. Bailey Joshua A. Betts Amy E. McCart Reed Kenneth P. Nephew Andrew Stone Julia M.W. Gee Dennis H. Dowhan Eloise Dray Annette M. Shewan Juliet D. French Stacey L. Edwards Susan J. Clark Sunil R. Lakhani Melissa A. Brown

Predicting response to endocrine therapy and survival in oestrogen receptor positive breast cancer is a significant clinical challenge and novel prognostic biomarkers are needed. Long-range regulators of gene expression are emerging as promising biomarkers and therapeutic targets for human diseases, so we have explored the potential of distal enhancer elements of non-coding RNAs in the prognost...

2014
Brennan Decker Elaine A Ostrander

Prostate cancer (PC) is the most common noncutaneous cancer in men, and epidemiological studies suggest that about 40% of PC risk is heritable. Linkage analyses in hereditary PC families have identified multiple putative loci. However, until recently, identification of specific risk alleles has proven elusive. Cooney et al used linkage mapping and segregation analysis to identify a putative ris...

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