نتایج جستجو برای: founder effect
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Prepublished online November 2, 2004; Schindler, Helmut Hanenberg, Shirley V Hodgson, Christopher G Mathew and Jordi Surralles Angeles Dasi, Jesus M Estella, Arturo Munoz, Juan J Ortega, Johan de Winter, Hans Joenje, Detlev Elsa Callen, Jose A Casado, Marc D Tischkowitz, Juan A Bueren, Amadeu Creus, Ricard Marcos, prevalence of Fanconi anemia in gypsy families from Spain underlies the world hig...
Genetic association studies have explained only a small proportion of the estimated heritability of complex traits, leaving the remaining heritability "missing." Genetic interactions have been proposed as an explanation for this, because they lead to overestimates of the heritability and are hard to detect. Whether this explanation is true depends on the proportion of variance attributable to g...
We have used mutations in the newly identified gene myoblast city to investigate the founder cell hypothesis of muscle development in Drosophila melanogaster. In embryos mutant for myoblast city the fusion of myoblasts into multinucleate muscles is virtually abolished. Nevertheless, a subset of the myoblasts develop specific muscle-like characteristics, including gene expression appropriate to ...
Spinocerebellar ataxia type 6 (SCA6) is one of multiple autosomal dominant progressive ataxias due to unstable trinucleotide repeat gene sequences. Overall prevalence of SCA6 is estimated to be 5:100,000 [1]. Carrier rates of the full-penetrance allele vary by geographic location, presumably due to founder effect, with the highest frequency observed in Japan (about 30%) followed by the United S...
the dynamism of the verity proposition has led to its being used in various issues and sciences as the founder for the general and constant principles. the principles of jurisprudence, as a science that is the founder for general rules to arrive at legal rulings, utilizes this proposition in many subdivisions of uṣūl (principles) as well as in resolving problems. in fact, if we do not take the ...
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