background: the differences between marginal gingiva and interdental papilla may be due to variation in the molecular composition of these two different anatomical structures. the aim of this study was to evaluate the staining intensity of fibronectin in human marginal gingiva and interdental papilla. materials and methods: in a prospective analytical study, 16 healthy subjects needing crown le...

OBJECTIVE To validate optical coherence tomography (OCT) imaging for assessment of vascular healing in a preclinical animal model and human autopsy cases and to translate the findings to the assessment of vascular healing after drug-eluting stent implantation in clinical practice. APPROACH AND RESULTS Drug-eluting and bare metal stents were imaged 28 and 42 days after implantation in atherosc...

thirty six wistar albino rats with implant induced endometriosis were randomly divided into six groups of six animals each. the rats in the first group received nothing and were euthanized at day 21. in the second group, rats received nothing and were euthanized at day 36. the third group received atorvastatin (atv; 5 mg kg-1 per day, orally) until 21 days from induction of endometriosis, and t...

Clear nosed skate, Raja erinacea were exposed to 0.10 (control), 0.52 or 1.73 microM copper and sculpin, Myoxocephalus octodecemspinosus were exposed to 0.10 or 1.73 microM copper (as CuSO4) in Salisbury Cove seawater for up to seven days. Skate gill copper concentrations increased 40-50 fold over background in response to copper exposure at both concentrations. In comparison, sculpin gill leve...

The chemosensory roles of gill neuroepithelial cells (NECs) in mediating the hyperventilatory response to hypoxia are not clearly defined in fish. While serotonin (5-HT) is the predominant neurotransmitter in O(2)-sensitive gill NECs, acetylcholine (ACh) plays a more prominent role in O(2) sensing in terrestrial vertebrates. The present study characterized the developmental chronology of potent...

Quantitative whole-body autoradiography was used to assess the distribution and tissue penetration of isavuconazole in rats following single and repeated oral-dose administration of radiolabeled isavuconazonium sulfate, the prodrug of isavuconazole. Following a single-dose administration of radiolabeled isavuconazonium sulfate (labeled on the active moiety), radioactivity was detectable within ...

purpose: to determine the dissection level during deep lamellar keratoplasty (dalk) using the big-bubble technique by light microscopy (lm) and transmission electron microscopy (tem). methods: descemet’s membrane (dm) and stromal tissue of 4 keratoconic eyes were removed because of inadvertent intraoperative dm perforation during dalk which was converted to penetrating keratoplasty. these speci...

Procedures were developed to isolate basolateral membrane vesicles (BLMV) from gill, hepatopancreas, and antennal gland of intermolt freshwater crayfish, Procambarus clarkii. Individual procedures involved a discontinuous sucrose gradient (gill), a 65% sucrose cushion (hepatopancreas), or differential centrifugation (antennal gland). BLMV were visualized, characterized (37°C), and tested for os...

STATEMENT OF THE PROBLEM Correct proportioning and mixing are essential to ensure cements attain their optimum physical properties. PURPOSE The aim of this experimental study was to evaluate the influence of various mixing techniques including manual, mechanical mixing, and ultrasonic vibration on push-out bond strength of calcium enriched mixture (CEM). MATERIALS AND METHOD Ninety 2-mm-thi...

Hypoxia (low oxygen) often occurs in aquatic ecosystems that receive effluent from municipal wastewater treatment plants (WWTP). The combination of hypoxia and WWTP could impair fish health, because contains multiple contaminants disrupt the physiological pathways use to cope with hypoxia, but interactive effects these stressors on physiology are poorly understood. We have examined this issue b...