In this supplement, we demonstrate statistical group analysis (diseased versus control) pipeline on a population of synthetically generated 2-D FDG-PET scans where the images are not brought into perfect alignment prior to analysis. We seek to demonstrate that our algorithm is able to still pick up the synthetically introduced group-level differences. We compare the results from the standard ap...

FDG-PET imaging has significantly altered the workup of the oncologic patient. With the introduction of combined FDG-PET/CT scanners, there has been a dramatic improvement in lesion detection, lesion characterization and accurate lesion localization. As attenuation correction can be attained with the CT images, PET exam times have been dramatically reduced, by as much as 50% in many instances. ...

UNLABELLED This work addresses the clinical adoption of FDG-PET/CT for image-guided radiation therapy planning (RTP). As such, important technical and methodological aspects of PET/CT-based RTP are reviewed and practical recommendations are given for routine patient management and clinical studies. First, recent developments in PET/CT hardware that are relevant to RTP are reviewed in the contex...

Alveolar echinococcosis: correlation between MRI aspect of hepatic lesions and the metabolic activity visualized in FDG-PET/CT Azizi Amel, Blagosklonov Oleg, Lounis Ahmed, Berthet Louis, Vuitton Dominique A., Bresson-Hadni Solange, Delabrousse Eric........................................................................................................................................................

Molecular imaging with PET is a rapidly emerging technique. In breast cancer patients, more than 45 different PET tracers have been or are presently being tested. With a good rationale, after development of the tracer and proven feasibility, it is of interest to evaluate whether there is a potential meaningful role for the tracer in the clinical setting-such as in staging, in the (early) predic...

There are several studies on 18F-FDG PET in the evaluation of musculoskeletal infection; however, a search of the literature failed to identify any large-scale studies. The 7 articles reviewed included 273 cases of suspected musculoskeletal infection evaluated by 18F-FDG PET. This method was found to be sensitive and specific in the evaluation of chronic and acute osteomyelitis and prosthetic i...

BACKGROUND Positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) is now a routine procedure for the management of cancer patients. Intravenous administration of FDG is sometimes halted due to troubles. In such cases, estimations of the FDG dosage injected prior to halting administration may be helpful. We have established a method of estimating the activity of FDG to patients on ...

We report a case of an 85-year-old woman with a foreign-body granuloma which accumulated 18F-fluorodeoxyglucose (FDG). Unenhanced computed tomography showed a hyperdense mass with a hypodense rim in the right subphrenic space. FDG PET/CT images showed intense FDG uptake in the hypodense rim and little FDG uptake in the center of the mass, showing a ring-shaped appearance. The fusion imaging of ...

OBJECTIVE We describe the significance of detecting focal areas of hypermetabolism in the breast in patients undergoing PET/CT for reasons other than for breast cancer detection or staging. CONCLUSION When evaluated, almost all of the abnormal foci detected in the breast subsequently proved to be breast carcinoma, specifically infiltrating ductal carcinoma.

UNLABELLED The objective of this pilot project was to devise a new image acquisition and processing technique to produce PET/CT images rendered in 3-dimensional (3D) volume that can then be reviewed in several 3D formats such as virtual bronchoscopy and colonoscopy "fly-throughs" and external "fly-arounds." METHODS We tested the new imaging and processing protocol on 24 patients with various ...