Uranium concentration in forty-six groundwater samples collected from the region near uranium deposits Royal village of Sikar district, Rajasthan, is determined using LED fluorimetry technique. Age-dependent annual effective dose, radiological, and chemical toxicity risks are calculated to assess health associated with for people living nearby area. concentrations different vary 4.79–266.28 µg/...

The Chinese Foundation of Health, Neonatal Screening Center, Taipei, Taiwan Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan Department of Pediatrics, Taipei Veterans General Hospital, Taipei, Taiwan Institute of Environmental and Occupational Health Sciences, National Yang-Ming University Depts. of Chemistry and Biochemistry, University of Washington, Seattle, WA 9...

Voltage-gated potassium (Kv) channel gating involves complex structural rearrangements that regulate the ability of channels to conduct K(+) ions. Fluorescence-based approaches provide a powerful technique to directly report structural dynamics underlying these gating processes in Shaker Kv channels. Here, we apply voltage clamp fluorimetry, for the first time, to study voltage sensor motions i...

Treatment against tuberculosis can lead to the selection of drug-resistant Mycobacterium strains. To tackle this serious threat, new targets from M. are needed develop novel effective drugs. In work, we aimed provide a possible workflow validate and inhibitors by combining genetic, in silico, enzymological approaches. CanB is one three β-carbonic anhydrases that catalyze reversible reaction CO2...