نتایج جستجو برای: fluctuation hypothesis fh
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To identify epigenetic patterns, which may predispose to type 2 diabetes (T2D) due to a family history (FH) of the disease, we analyzed DNA methylation genome-wide in skeletal muscle from individuals with (FH(+)) or without (FH(-)) an FH of T2D. We found differential DNA methylation of genes in biological pathways including mitogen-activated protein kinase (MAPK), insulin, and calcium signaling...
Pneumococcal surface protein C (PspC) binds to both human secretory immunoglobulin A (sIgA) and complement factor H (FH). FH, a regulator of the alternative pathway of complement, can also mediate adherence of different host cells. Since PspC contributes to adherence and invasion of host cells, we hypothesized that the interaction of PspC with FH may also mediate adherence of pneumococci to hum...
Heterozygous familial hypercholesterolemia (FH) is an autosomal dominant disorder known to be associated with elevated cholesterol levels and increased risk of premature coronary heart disease. Since increased cholesterol levels lead to atherosclerosis, FH has also been proposed as a risk factor for peripheral vascular and ischemic cerebrovascular disease. Currently, the association between cli...
Investigations on diffusion in systems with memory [1] have established a hierarchical connection between mixing, ergodicity, and the fluctuation-dissipation theorem (FDT). This hierarchy means that ergodicity is a necessary condition for the validity of the FDT, and mixing is a necessary condition for ergodicity. In this work, we compare those results with recent investigations using the Lee r...
مقدمه: تست حداکثر ظرفیت ورزشی می تواند به عنوان یک تست تشخیصی در بیماران با مشکلات قلبی و عروقی بدون علائم کلینیکی در نظر گرفته شود. کمبود هورمون های تیروئیدی در دوره جنینی می تواند منجر به کاهش عملکرد سیستم قلبی عروقی شود. هدف از این مطالعه، ارزیابی میزان حداکثر ظرفیت ورزشی در زادههای بالغ مبتلا به هیپوتیروئیدی جنینی (fh) در موش صحرائی میباشد. روش ها: fh بوسیله اضافه کردن داروی پروپیل تیوا...
This work focuses on developing and characterizing a statistic for testing contrasts among population effects and developing confidence regions for those effects using data from longitudinal studies. Historically, likelihood ratio or Wald-type statistics were used for such analyses, but those statistics produce very optimistic Type I error rates. McCarroll and Helms (1987) introduced an ad hoc ...
The aim of this article is to quantify and analyze mutual interference of Frequency Hopping with Collision Avoidance (FH/CA) systems. The FH/CA system is a frequency hopping system where stations select the least jammed channel from several possible before the next jump. The article describes a mathematical model that allows determining the upper limit of the probability of collision of multipl...
BACKGROUND Lymphoid aggregates are normally found throughout the small and large intestine. Known as lymphoid nodular hyperplasia (LNH), these aggregates are observed especially in young children and are not associated with clinical symptoms being considered 'physiological'. In children presenting with gastrointestinal symptoms the number and size of the lymphoid follicles are increased. Patien...
Familial hyperaldosteronism type II (FH-II) is characterized by autosomal dominant inheritance and hypersecretion of aldosterone due to adrenocortical hyperplasia or an aldosterone-producing adenoma; unlike FH type I (FH-I), hyperaldosteronism in FH-II is not suppressible by dexamethasone. Of a total of 17 FH-II families with 44 affected members, we studied a large kindred with 7 affected membe...
BACKGROUND AND PURPOSE Positive family history (FH+) of cardiovascular disease (CVD) is a risk factor for own CVD. We aimed to analyze the effect of different types of FH (stroke, coronary heart disease (CHD), peripheral artery disease (PAD) on carotid intima-media thickness (cIMT) in young and middle-aged ischemic stroke patients. METHODS First-degree FH of CVD was assessed in ischemic strok...
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