BACKGROUND Genetic modifications can improve the therapeutic efficacy of mesenchymal stem cell (MSC) transplantation in myocardial infarction. However, so far, the efficiency of MSC modification is very low. Seeking for a more efficient way of MSC modification, we investigated the possibility of employing the intercellular trafficking capacity of the herpes simplex virus type-1 tegument protein...

Abstract Hypothesis The implementation of the proposal from European Chemical Agency (ECHA) to restrict use nanoplastics (NP) and microplastics (MP) in consumer products will require reliable methods perform size mass-based concentration measurements. Analytical challenges arise at nanometre micrometre interface, e.g., 800 nm–10 µm, where techniques applicable scale reach their upper limit appl...

Abstract Background B lymphocyte activating factor (BAFF) is a growth regulating lymphocytes survival and maturation. Serum BAFF levels were elevated in patients affected with autoimmune thyroid diseases (AITD), including Graves’ disease (GD) Hashimoto’s thyroiditis (HT). The aim of this study to explore the association expression its receptors AITD. Methods Fifty-two GD patients, 39 (HT) 23 he...

objective:at the present study, relationship between phagocytosis of plga particles and combined effects of particle size and surface pegylation was investigated.  materials and methods:microspheres and nanospheres (3500 nm and 700 nm) were prepared from three types of plga polymers (non-pegylated and pegylation percents of 9% and 15%). these particles were prepared by solvent evaporation metho...

Background Increasing epidemiological, clinical, and experimental evidence suggests that Alzheimer’s disease (AD) pathogenesis is closely associated with systemic abnormalities, including dynamic processes in the peripheral immune compartment inflammation1,2,3. Recent reports transgenic AD animal models propose a role of dysregulated system memory impairment4,5. In this regard, contribution res...