Type-1 diabetes (T1D) is a metabolic disorder associated with massive reduction in mass of adipose tissue. Measuring cell diameter, an index of fat metabolism, we determined depot-specific alterations in weight of adipose tissue, fat cell diameter and size heterogeneity and distribution at 5 depots in streptozotocin (STZ)-induced diabetic rats. T1D was induced by a single injection of STZ. Seve...

OBJECTIVE To measure the effect of 24 months of depot medroxyprogesterone acetate use on bone mineral density compared with oral contraception (pills) and nonhormonal contraception. METHODS Women aged 18-33 years self-selected oral contraception, depot medroxyprogesterone acetate, or nonhormonal contraception (controls). Those selecting pills were randomized to formulations containing either ...

Abstract We apply the concept of servo constraints to end-effector trajectory tracking control parallel robots with structural link flexibilities. Such deliver inverse robot model where solution approaches via projections are proposed, which transform resulting differential-algebraic equations ordinary differential equations. The applicable process depends on existence and stability internal dy...

Differences in the inherent properties of adipose tissue-derived stem cells (ASC) may contribute to the biological specificity of the subcutaneous (Sc) and visceral (V) adipose tissue depots. In this study, three distinct subpopulations of ASC, i.e. ASCSVF, ASCBottom, and ASCCeiling, were isolated from Sc and V fat biopsies of non-obese subjects, and their gene expression and functional charact...

Hormonally induced azoospermia induced by weekly im injections of testosterone enanthate provides effective and reversible male contraception, but more practical regimens are needed. Given our previous findings that six 200-mg pellets implanted subdermally produced more stable, physiological T levels and reduced the delivered T dose by more than 50% while maintaining equally effective suppressi...

A st act.—During migration, many songbirds eat primarily fruit while depositing fat. Given that some fruits contain mostly carbohydrate and others contain mostly lipid, the ability of birds to fatt en may depend on the macronutrient composition of the fruit. Stable isotopes of carbon may be useful in determining the source of nutrients used for synthesizing fat, because the enzyme that regulate...

CONTEXT Treatment of adult GH deficiency (AGHD) with daily injections of GH results in decreased adipose mass, increased lean body mass (LBM), increased bone mineral density, and improved quality of life. OBJECTIVE This study seeks to determine whether a depot preparation of GH given every 14 d would lead to comparable decreases in trunk adipose tissue as daily GH. DESIGN This open-label, r...

In this research discusses the problem of distributing goods from a depot to several customer locations minimize travel costs. The is solved by using Vehicle Routing Problem method. data used in secondary with 10 customers and one depot. aim form model that has been obtained determine optimal route based on formed. first step objective function problem, then constraints may occur. After formed,...

We consider a two-echelon inventory system where the exogenous demands occur only at the retailer locations, and the demand rates are functions of an underlying continuoustime Markov chain. This underlying process may represent, for example, general economic conditions, the number of active users in the system, etcetera. Each retailer location follows a base-stock policy that is independent of ...

This paper aims to study the locomotive assignment problem which is very important for railway companies, in view of high cost of operating locomotives. This problem is to determine the minimum cost assignment of homogeneous locomotives located in some central depots to a set of pre-scheduled trains in order to provide sufficient power to pull the trains from their origins to their destinations...