نتایج جستجو برای: flavones
تعداد نتایج: 1217 فیلتر نتایج به سال:
Natural polyphenol compounds are often good antioxidants, but they also cause damage to cells through more or less specific interactions with proteins. To distinguish antioxidant activity from cytotoxic effects we have tested four structurally related hydroxyflavones (baicalein, mosloflavone, negletein, and 5,6-dihydroxyflavone) at very low and physiologically relevant levels, using two differe...
Flavone compounds present as secondary metabolites in many plants have beneficial phytochemical activity. Isolation of flavones from various parts has been widely carried out, but the synthesis pathway is another way to obtain higher yields. This research aimed synthesize flavone vanillin and 2-hydroxyacetophenone through chalcone intermediates produce a 74% yield using an iodide catalyst. new ...
A low cost, safe, clean and environmentally benign base-catalyzed cyclodehydration of appropriate β-diketones affording (E)-2-styrylchromones and flavones in good yields is disclosed. Water was used as solvent and the reactions were heated using classical and microwave heating methods, under open and closed vessel conditions. β-Diketones having electron-donating and withdrawing substituents wer...
Kinase Suppressor of Ras (KSR) is a molecular scaffold that interacts with the core kinase components of the ERK cascade, Raf, MEK, ERK to provide spatial and temporal regulation of Ras-dependent ERK cascade signaling. Interruption of this mechanism can have a high influence in inhibiting the downstream signaling of the mutated tyrosine kinase receptor kinase upon ligand binding. Still none of ...
Flavones are belonging to flavonoids group and show diverse biological functions. Therefore, they have much attention as drugs for maintaining human health via contributing prevention treatment of various diseases like cancers, diabetes, neurodegenerative diseases, ischemic stroke, inflammation cardiovascular diseases. On the other hand, monoblastic leukemia U937 cells been used an excellent in...
Abstract The Urticaceae family, circumscribed within the Rosales, was investigated in this study with an overview of current literature about phytochemical studies using Liquid Chromatography coupled to Mass Spectrometry (LC-MS) technique. aim review secondary metabolites identified Urticaeae LC-MS analysis. A systematic performed Scifinder and ScienceDirect databases. Phenolic substances are m...
Flavones are synthesized from flavanones through the action of flavone synthases (FNSs). There are two FNSs, FNS I and II. FNS I is a soluble dioxygenase present in members of the Apiaceae family and FNS II is a membrane bound cytochrome P450 enzyme that has been identified in numerous plant species. In this study, we cloned OsFNS I-1 from rice by RTPCR, expressed it in E. coli, and purified th...
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