OBJECTIVE To assess the efficacy of enzyme potentiated desensitisation in the treatment of severe summer hay fever poorly controlled by pharmacotherapy. DESIGN Double blind randomised placebo controlled parallel group study. SETTING Hospital in Hampshire. PARTICIPANTS 183 participants aged between 18 and 64 with a history of severe summer hay fever for at least two years; all were skin pr...

In the past, reluctance to determine the serum magnesium level in the newborn infant has been due in part to the relative unreliability of methods hitherto employed (Wacker and Vallee, 1958), and the need for large amounts of blood, particularly where repeat determinations are proposed. In 1964 Rice and Lapara described a rapid, accurate ultramicro method for the determination of ionic magnesiu...

Informed investors are a source of illiquidity, but those pursuing di¤erently informed strategies also generate quasi -noise trading. Quasi-noise trading creates non-monotonic externalities in information choice that shape the composition of active investment and that in‡uence investor herding, liquidity spirals, asset comovement, along with the information content of prices. These externalitie...

I. Delayed Arrest of Rat Brain Slice Respiration Caused by Pentobarbital during the Metabolism of Glucose. J. L. Karisson, V. C. Sutherland and H. \V. Elliott 1 II. A Metabolite of Pamaquine from Chickens. Edward S. Josephson, Joseph Greenberg, I). Jane Taylor and H. L. Bami 7 11!. The Adrenergic Blocking Act ion of Some 1)ibenzazepine Derivatives. Lowell 0. Randall and Thomas 11. Smit Ii . 10 ...

J. Clin. Invest. © The American Society for Clinical Investigation, Inc. 0021-9738/96/03/1360/06 $2.00 Volume 97, Number 6, March 1996, 1360–1365 “Molecular Medicine in Genetically Engineered Animals” Series Editor, Kenneth R. Chien January 1 Gene modification via “plug and socket” gene targeting................................. Jada Lewis, Baoli Yang, Biological insights through genomics: mous...

In a commentary on an article by Geiselman, Bjork, and Fishman (1983), directed forgetting observed in the normal waking state is compared with amnesia as induced by hypnotic suggestion. The two paradigms typically differ with respect to the role of incidental or intentional learning, the amount of study devoted to the items, the temporal location of the cue to forget, the retention interval in...

A model of kiwifruit berry development is presented, building on the model of Fishman and Génard used for peach fruit. That model has been extended to incorporate a number of important features of kiwifruit growth. First, the kiwifruit berry is attached to the stem through a pedicel/receptacle complex which contributes significantly to the hydraulic resistance between the stem and the fruit, an...

This paper presents a theory of disclosure in a market where investors have heterogeneous beliefs and face short-sale constraints. Assets trade above fundamentals reflecting the value of the option to sell to more optimistic investors in the future. The initial seller has an incentive to commit to an imprecise disclosure policy, despite the negative effect this has on the fundamental value of t...

We consider a principal-agent model, in which the agent needs to borrow from the principal to finance a project. Our model is based on DeMarzo and Fishman (2003), except that the agent’s cash flows are given by a Brownian motion with drift in continuous time. The difficulty in writing an appropriate financial contract in this setting lies in the fact that the agent can hide cash flows and not p...

Objective The aim of this study was to establish the normative data of dentofacial transverse dimensions according to the skeletal maturation stage in Korean adolescents with good occlusion, assess gender differences and determine correlations between transverse variables. Methods A total of 577 Korean subjects between ages 7 to 19 years and exhibiting skeletal Class I occlusion were categori...