Images were acquired using micro tomography technique (μCT ). That technique allows to study nondestructive internal structures imaging of any object. X-ray tube generates x-ray electromagnetic radiation which penetrates through the studied sample. Attenuation of x-rays intensity is registered at the opposite side of the sample by two-dimensional detector. Value of x-ray intensity registered in...

Micro-rotation confocal microscopy is a novel optical imaging technique which employs dielectric fields to trap and rotate individual cells to facilitate 3D fluorescence imaging using a confocal microscope. In contrast to computed tomography (CT) where an image can be modelled as parallel projection of an object, the ideal confocal image is recorded as a central slice of the object correspondin...

PURPOSE We evaluated an off set reconstruction method for single photon emission computed tomography (SPECT), and compared it with the conventional on set reconstruction method, using sampling angles of 2, 4, and 6 degrees. METHOD A triple-detector system was used. In the off-set acquisition, sampling angles of the opposite detector were shifted 1/2 of the sampling angles of 2, 4, and 6 degre...

ABSTRACT Digital tomosynthesis mammography algorithms allow reconstructions of arbitrary planes in the breast from limitedangle series of projection images as the x-ray source moves along an arc above the breast. Though several tomosynthesis algorithms have been proposed, no complete comparison of the methods has previously been conducted. This paper presents an analysis of impulse response for...

Spectral analysis is a general modelling approach that enables calculation of parametric images from reconstructed tracer kinetic data independent of an assumed compartmental structure. We investigated the validity of applying spectral analysis directly to projection data motivated by the advantages that: (i) the number of reconstructions is reduced by an order of magnitude and (ii) iterative r...

Stationary digital breast tomosynthesis (sDBT) with distributed X-ray sources based on carbon nanotube (CNT) field emission cathodes has been recently proposed as an approach that can prevent motion blur produced by traditional DBT systems. In this paper, we simulate a geometric calibration method based on a proposed multi-source CNT X-ray sDBT system. This method is a projection matrix-based a...

Statistical image reconstruction (SIR) methods have shown potential to substantially improve the image quality of low-dose X-ray computed tomography (CT) as compared to the conventional filtered back-projection (FBP) method. According to the maximum a posterior (MAP) estimation, the SIR methods can be typically formulated by an objective function consisting of two terms: (1) data-fidelity (or e...