Desmoplastic fibroblastoma (DF) is a rare benign fibroblastic soft tissue tumor.1 The tumour is prevalent in adult men (4:1), aged 50 to 60 years, with wide anatomic distribution, and tipically it arises in the subcutaneous or subfascial tissue, mainly, of skeletal muscles. The tumor behaves in a benign fashion, presents a slowly growing with no recurrence or metastases, it can achieve a large ...

To determine the effects of transforming growth factor-beta (TGF-beta) on the different cell types that exist in bone, cell populations (I-IV), progressively enriched in osteoblastic cells relative to fibroblastic cells, were prepared from fetal rat calvaria using timed collagenase digestions. TGF-beta did not induce anchorage-independent growth of these cells, nor was anchorage-dependent growt...

Five cases of familial and idiopathic gingival fibromatosis were reported. One case exhibited peculiar histologic features, which consisted of active growth of the fibroblastic cells. One hundred and ninety-six cases of gingival fibromatosis, whose clinical and/or pathologic findings were known, were collected from foreign literatures. The heterogeneity in gingival fibromatosis was discussed.

DEFINITION The histopathologic characteristics of ECD overlap xanthogranuloma and distinctions between the two are made on clinical and radiologic findings. Lipid-laden histocytes with foamy or eosinophilic cytoplasm infiltrate bones and various organs and generate a fibroblastic response that leads to critical organ failure. The histocytes are CD68+, Factor XIIIa+ CD1a-, S100-, and lack Birbec...

Two 48-h Vero cell systems were compared with viral culture in human fibroblastic cells for isolation and identification of herpes simplex virus from clinical specimens. Both 48-h systems had 79% sensitivity and greater than 99% specificity as compared with the conventional tissue culture method.

Two new cell lines (CCF and CCH) were established from fin and heart tissues of common carp, Cyprinus carpio. The cells were optimally maintained in Leibovitz-15 medium supplemented with 10% fetal bovine serum (FBS) and 10 ng/ml of basic fibroblastic growth factor (bFGF). The effects of temperature, concentration of FBS and bFGF on the growth of CCF and CCH cells were examined. The temperature ...