We report a step toward scanning endomicroscopy without distal optics. The focusing of the beam at the distal end of a fiber bundle is achieved by imposing a parabolic phase profile across the exit face with the aid of a spatial light modulator. We achieve video-rate images by galvanometric scanning of the phase tilt at the proximal end. The approach is made possible by the bundle, designed to ...

In this paper, we present a novel approach for the segmentation of white matter tracts based on Finsler active contours. This technique provides an optimal measure of connectivity, explicitly segments the connecting fiber bundle, and is equipped with a metric which is able to utilize the directional information of high angular resolution data. We demonstrate the effectiveness of the algorithm f...

We prove that the L metric on the direct image of an adjoint positive line bundle by a locally trivial submersion between projective manifolds is Nakano positive, under the assumption that the typical fiber has zero first Betti number. As a consequence, we get that the symmetric powers of an ample vector bundle tensorized by its determinant are Nakano positive, in particular Griffiths positive....

We present an extension of fiber bundle models considering that failed fibers still carry a fraction 0 < or = alpha < or = 1 of their failure load. The value of alpha interpolates between the perfectly brittle failure (alpha = 0) and perfectly plastic behavior (alpha = 1) of fibers. We show that the finite load bearing capacity of broken fibers has a substantial effect on the failure process of...

An intravenous respiratory support catheter, the next generation of artificial lungs, is being developed in our laboratory to potentially support acute respiratory failure or patients with chronic obstructive pulmonary disease with acute exacerbations. A rapidly pulsating 25 ml balloon inside a bundle of hollow fiber membranes facilitates supplemental oxygenation and CO2 removal. In this study,...

Experimental studies have shown that biventricular pacing can improve systolic function in the failing heart with bundle branch block. The goal of this study was to develop and validate a three-dimensional computational model of the dilated failing heart with left bundle branch block to investigate how biventricular pacing can improve systolic mechanical performance and synchrony. In an anatomi...

Braided composites have been used widely in many engineering fields where the high mechanical characteristics and light weight properties were important. In order to estimate the mechanical characteristics of the braided composites, the numerical technique is very effective to reduce the testing and production costs. However, if the architecture of fiber bundle is more complex such as 3-D braid...

A paracorporeal respiratory assist lung (PRAL) is being developed for supplemental gas exchange to allow the native lungs of acute lung failure patients to heal. The device consists of a rotating annular microporous hollow fiber membrane bundle. The rotation augments the gas exchange efficiency of the device at constant flow-rate thereby uncoupling gas exchange and flow rate. The rotating fiber...

This paper reviews basic methods and recent applications of length-based fiber bundle analysis of cerebral white matter using diffusion magnetic resonance imaging (dMRI). Diffusion weighted imaging (DWI) is a dMRI technique that uses the random motion of water to probe tissue microstructure in the brain. Diffusion tensor imaging (DTI) is an extension of DWI that measures the magnitude and direc...