INTRODUCTION Fever of unknown origin (FUO) is a common initial presentation leading to a diagnostic challenge. PATIENT CONCERNS A 3-month history of moderate-to-high fever was reported in an otherwise healthy 54-year-old man. Enhanced computed tomography (CT) scans of his chest showed a remarkable progressive enlargement of bilateral cervical, supraclavicular, hilar, and mediastinal lymph nod...

Dengue has been reported from plains as well as hilly regions of India including some parts of Northeast India. In July-August 2012, outbreak of fever with unknown origin (FUO) indicative of Dengue was reported in Pasighat, East Siang district of Arunachal Pradesh (AP) state. Serum samples (n = 164) collected from patients from Health Training and Research Centre General Hospital, Pasighat, wer...

Introduction Fever of unknown origin (FOU) i.e.: (1) a temperature greater than 38.3°C on several occasions, (2) more than 3 weeks’ duration of illness, and (3) failure to reach a diagnosis despite 1 week of inpatient investigation are commonly seen in pediatric practice. The conditions could be caused by mutations of genes coding inflammasome sequences. In these instances activated neutrophils...