The relations between pulsatile pressures and flows in the umbilico-placental circulation have been investigated using chronically instrumented fetal sheep. Under resting conditions, mean arterial pressure fell by 30 +/- 6%, from 44 +/- 2 to 31 +/- 2 mm Hg between the aortic termination and the arteries feeding the cotyledons, and pressure waves were substantially damped during propagation betw...

introduction:maternal diabetes mellitus is associated with depleted fetal iron stores and this is proportionate to the degree of maternal control, presence or absence of diabetes-related complications, and is not related to maternal iron status. in this study, we aim to assess the effect of maternal diabetes on cord blood serum ferritin. methods: the present prospective (case-control) study was...

background & aim: gestational diabetes is a medical condition that can lead to adverse outcomes of pregnancy. in this regard, the best way to reduce symptoms can be patient education. hence, the aim of this study was to determine the effects of face-to-face training and booklet-based education on the maternal outcomes of diabetes in pregnancy. methods & materials: a total of 126 patients with g...

objective: the use of fetal hemoglobin (hbf) inducer drugs is considered as a novel approach in treatment of β-hemoglobinopathies, especially β- thalassemia and sickle cell disease. hbf inducers including hydroxyurea, histone deacetylase (hdac) inhibitor agents such as sodium butyrate, azacitidine, decitabine and new immunomodulator drugs like pomalidomide, lenalidomide and thalidomide can redu...

background: pregnancy and accelerated fetal growth always are related with major metabolic changes and body fat redistribution and adiponectin is one of principle adipocyte hormones, so studying adiponectin changes during pregnancy may reveal some hidden parts of fetal metabolism. the aim of this study was to assess adiponectin and leptin levels in umbili cal cord and maternal serum, their rela...

background: because of the adverse effects of ionizing radiation on fetuses, prior to radiotherapy of pregnant patients, fetal dose should be estimated. fetal dose has been studied by several authors in different depths in phantoms with various abdomen thicknesses (at). in this study, the effect of maternal at and depth in fetal dosimetry was investigated, using peripheral dose (pd) distributio...

background: the primary goal of antenatal testing is to identify fetuses at risk of intrauterine neurologic injury or death so that these adverse outcomes can be prevented. we want to assess nonstress test (nst) results and some parameters before and after vibro-acoustic stimulation and acupressure. we did a randomized controlled clinical trial in shahid-beheshti hospital in isfahan in 2011. ma...

background: methamphetamine (ma) is a potent psychomotor stimulant with high abuse and addictive potential. ma is a neurotoxic drug which is widely abused by females of childbearing age, raising serious public health concerns in terms of exposure of the fetus to the drug. neurotoxic effects of ma on adult are well known, such as dopaminergic nerve terminal degeneration and cell death in regions...

objective: the purpose of this study was to investigate the incidence, type, location, and risk factors of accidental fetal lacerations during caesarean delivery. material and methods: total deliveries, caesarean deliveries, and neonatal records for documented accidental fetal lacerations were reviewed retrospectively in four university hospital. thegestational age, the presenting part of the f...