نتایج جستجو برای: ferroxidase

تعداد نتایج: 334  

2014
Kyung-Tae Lee Jang-Won Lee Dohyun Lee Won-Hee Jung Yong-Sun Bahn

The iron uptake and utilization pathways play a critical role in allowing human pathogens, including Cryptococcus neoformans, the causative agent of fatal meningoencephalitis, to survive within the mammalian body by competing with the host for iron. Here we show that the iron regulon is also required for diverse environmental stress responses and that in C. neoformans, it is regulated by the hi...

Journal: :Molecular vision 2003
Lin Chen Tzvete Dentchev Robert Wong Paul Hahn Rong Wen Jean Bennett Joshua L Dunaief

PURPOSE Oxidative stress plays a role in the photic injury model of retinal degeneration and in age-related macular degeneration. Our preliminary microarray analysis of retinal gene expression upon photic injury suggested increased expression of ceruloplasmin, a ferroxidase that could reduce retinal oxidative stress. Patients with acerul oplasminemia have retinal degeneration, indicating that c...

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