OBJECTIVE To study the effect of induced hypothyroidism and thyroxin replacement on bone growth. DESIGN An animal study carried out on experimental Albino rats. PLACE AND DURATION OF STUDY The study was carried out in the Department of Anatomy, Basic Medical Sciences Institute (BMSI), Jinnah Postgraduate Medical Centre (JPMC), Karachi, from June 1999 to May 2002. METHOD Pregnant female Al...

I. Young adult female albino rats were given 20, 40, 60, 80, and 100% raw egg white powder in their diet; controls were fed on laboratory chow. Daily clinical measurements were made for z weeks. The rats were then killed, and the weights and water contents of various organs were determined. 2. The experiment was repeated with groups of young male albino rats fed for z and 4 weeks. 3. Toxic sign...

Background: The study was performed to the alterations in biochemical markers of liver and kidney function oxidative stress indices on sub-acute exposure meloxicam albino rats. Methods: three groups rats, consisting six rats each group. group I were served as control. However, II, III treated with @ 0.2 mg/kg b.wt. 0.6 respectively. Result: Meloxicam administration induced indicated by signific...

Introduction: Cyclophosphamide is one of the alkylating chemotherapeutic drug used in cancer patients that has antifertility effects on female gonads. Ocimum basilicum a natural herb rich polyphenols and known to improve fertility. Aims & Objectives: The study was designed evaluate role herb, extract, as preventive agent against ovarian follicular toxicity induced by cyclophosphamide. Place...

Huntingtons disease (HD) is an autosomal dominant neurodegenerative disease. Accordingly, 3-nitropropionic acid (3-NP) has been found to effectively produce HD-like symptoms. Amaranthus viridis Linn (HAEAV), popularly known in Chauraiya Hindi, may act as a neuroprotective agent vitro andin vivo. We evaluated the hypothesis that hydro-ethanolic extract of could prevent behavioral and oxidative a...

objective(s):one cause of cigarette smoking is oxidative stress that may alter the cellular antioxidant defense system, induce apoptosis in lung tissue, inflammation and damage in liver, lung, and kidney. it has been shown that chinese green tea (cgt) (lung chen tea) has higher antioxidant property than black tea. in this paper, we will explore the preventive effect of cgt on cigarette smoke-in...

Aim: The interaction between obesity and increased production of pro-inflammatory cytokines results the existence inflammation HMGB1 secreted from adrenal gland can play a role in pathways. aim this study is to explain link gland. Material Methods: In study; eighteen female Wistar Albino rats were divided into two groups: untreated control group (n=8) obese (n=10). fed with high fat diet for te...

Objective: In this study, the effects of three different ozonated oils (Sesame, Nigella sativa, and Hypericum perforatum) on wound closure rate, healing process, possible complications were examined macroscopically microscopically. Materials Methods: Twenty-one adult Wistar albino female rats used in study. Subjects divided into groups, early healing, (7 days), medium (14 late (21 days). Four f...

Increasing use of mobile phones in daily life with increasing adverse effects electromagnetic radiation cause many concerns about their on human health. This study was designed to investigate the effect exposure a 900-MHz waves (EMW) produced by nucleic acids (DNA and RNA), protein content, kidney function (levels urea creatinine) oxidative stress (malondialdehyde, MDA level) rats before, durin...

Bisphenol-A is an estrogenic chemical used today in the production of epoxy resin and as additive other non-polymer plastics. Due to widespread use BPA today, human exposure inevitable. This causes harmful effects on various body systems. The aim this study investigate development kidneys offspring mother rats exposed during pregnancy lactation, a result being through placenta milk. In study, 1...