corticosterone in male and female virgin and breeder rats. Acta Endocrinol 62: 411-424, 1969 14. lams SG, Wexler BC: Aldosterone, deoxycorticosterone and corticosterone differences between arteriosclerotic breeder vs nonarteriosclerotic virgin rats. Atherosclerosis 24: 63-73, 1976 15. Wexler BC, True CW: Carotid and cerebral arteriosclerosis. Circ Res 12: 659-666, 1963 16. Wexler BC: Spontaneou...

Intramuscular injection of nerve growth factor (NGF) into rat masseter muscle induces a local mechanical sensitization that is greater in female than in male rats. The duration of NGF-induced sensitization in male and female rats was associated with an increase in peripheral N-methyl-d-aspartate (NMDA) receptor expression by masseter muscle afferent fibers that began 3 days postinjection. Here,...

The present study investigated the effect of starvation-refeeding status on cholesterol metabolism in rats fed a high-cholesterol diet or a cholesterol-free diet. Twenty male and 20 female Donryu rats (age 5 weeks) were fed a cholesterol-free diet for 14 days. Then the male and female rats were each divided into two groups: feeding and starvation-refeeding groups. The feeding groups were fed th...

Twenty-one days of restraint stress has been shown to affect hippocampal plasticity, neurogenesis, and spatial memory. Hippocampal glucocorticoid receptors (GR) and mineralocorticoid receptors (MR) are the main mediators of stress response and learning/memory processes. We studied the performance of male and female rats on a hippocampal-dependent spatial task after 21 days of restraint in relat...

Evidence shows that tryptophan (TRP) and serotonin (5HT) have a role in memory function. It has been shown in various studies that increase in serotonergic neurotransmission is associated with increased memory consolidation whereas low brain 5HT impairs memory performance. In view of a possible role of TRP and 5HT in memory, the present study was designed to investigate the effect of TRP supple...