Tritrichomonas suis (=T. foetus) has recently been reported to be a causative agent of chronic large-bowel diarrhea in cats. While the disease was previously attributed to Pentatrichomonas hominis, the etiologic agent for feline trichomonal diarrhea was identified as T. suis. Although feline trichomonosis due to T. suis has been reported at prevalences ranging from 14 to 31% in Europe and the U...

It is estimated that 2.5 million cats enter animal shelters in the United States every year and as few as 20% leave the shelter alive. Of those adopted, the greatest risk to post-adoption human animal bond is unrealistic expectations set by the adopter. The ASPCAr’s Meet Your Matchr Feline-alityTM adoption program was developed to provide adopters with an accurate assessment of an adult cat’s f...

Canine parvovirus (CPV) and feline panleukopenia virus (FPV) capsids bind to the transferrin receptors (TfRs) of their hosts and use these receptors to infect cells. The binding is partially host specific, as FPV binds only to the feline TfR, while CPV binds to both the canine and feline TfRs. The host-specific binding is controlled by a combination of residues within a raised region of the cap...

Objectives Feline leukaemia virus (FeLV), a gamma retrovirus, causes diseases of the feline haematopoietic system that are invariably fatal. Rapid and accurate testing at the point-of-need (PON) supports prevention of virus spread and management of clinical disease. This study evaluated the performance of an insulated isothermal PCR (iiPCR) that detects proviral DNA, and a reverse transcription...

Introduction AGP (Alpha1-acid glycoprotein) is considered one of the major acute phase proteins in cats. In humans, AGP is a heavily glycosylated protein that undergoes several modifications of its glycan moiety during acute and chronic inflammatory pathologies. In this communication we present the feline AGP’s glycan moiety modifications in the course of two very frequent feline diseases, the ...

A synthetic feline TRIM5-cyclophilin A fusion protein (feTRIMCyp) was generated and transduced into feline cells. feTRIMCyp was highly efficient at preventing infection with human (HIV) and feline (FIV) immunodeficiency virus pseudotypes, and feTRIMCyp-expressing cells resisted productive infection with either FIV-Fca or FIV-Pco. The restriction of FIV infection by feTRIMCyp was reversed by the...

A serosurvey of feline herpesvirus type 1 (FHV-1), feline calicivirus (FCV), and feline parvovirus (FPV) in cats from Ho Chi Minh City area in southern Vietnam was conducted in December 1998, and we compared the results with our previous results in northern Vietnam (Hanoi area). The positive rate of FHV and FCV in domestic cats were 44% and 74%, respectively. They were rather higher than those ...

Negative FIV-antibody test results remain reliable (see the 2001 Report of the AAFP/AFM Advisory Panel on Feline Retrovirus Testing and Management at www.aafponline.org/resources/guidelines/Felv_FIV_Guidelines.pdf. But until tests that differentiate vaccinated cats from infected cats become readily available, it will be impossible to assess the significance of positive test results. (Is a posit...