Various PET studies, such as measurements of glucose, serotonin and oxygen metabolism, cerebral blood flow and receptor bindings are availabe for epilepsy. (18)Fluoro-2-deoxyglucose ((18)F-FDG) PET imaging of brain glucose metabolism is a well established and widely available technique. Studies have demonstrated that the sensitivity of interictal FDG-PET is higher than interictal SPECT and simi...

Fluorodeoxyglucose positron emission tomography (FDG-PET) imaging based 3D topographic brain glucose metabolism patterns from normal controls (NC) and individuals with dementia of Alzheimer’s type (DAT) are used to train a novel multi-scale ensemble classification model. This ensemble model outputs a FDG-PET DAT score (FPDS) between 0 and 1 denoting the probability of a subject to be clinically...

UNLABELLED The aim of this study was to compare the value of reviewing combined 18F-FDG PET/CT images with that of reviewing side-by-side PET and CT images in the diagnosis of locoregional lymph node metastases in patients with esophageal squamous cell cancer. METHODS From November 2003 to December 2005, 45 patients with thoracic esophageal squamous cell cancer underwent 18F-FDG PET/CT before...

Received 1/8/2002; accepted 1/17/2002. For correspondence or reprints contact: Pan-Fu Kao, M.D., Department of Nuclear Medicine, Chang Gung Memorial Hospital and Chang Gung University, 199 Tung Hwa North Road, Taipei 105, Taiwan, R.O.C. Tel: (886)3-3281200 ext. 2622, Fax: (886)3-3282619, E-mail: [email protected] Background: Fluor ine-18-2-deoxy-D-glucose ([F]FDG) has been widespread use...

UNLABELLED Injecting drug use (IDU) is a major risk factor for contracting HIV-1 infection. Both HIV and IDU are neurotoxic, and their coexistence may lead to increased dysfunction of brain metabolic processes. The objective of this research was to investigate the effects of HIV-1 infection and IDU on (18)F-FDG PET brain metabolism. METHODS (18)F-FDG PET brain imaging, with a standard clinica...

Despite recent advances in medical and surgical treatments to prevent arterial stroke, the cerebrovascular burden of atherosclerosis remains high. Factors associated with a high risk for arterial stroke include stenosis .50% and ulcerated plaque. Given the important role of inflammation in atherosclerotic plaque progression and rupture, a measure of plaque inflammation may help stratify arteria...

Methods Twenty-one combined FDG-GaTate studies were performed in various NETs lineages. A retrospective blinded review was performed based on the grade of tumour differentiation of ki-67 (European NET Society-ENETS) and the correlated Krenning scales (Grade 1-4) of the FDGGaTATE PET-CT images. Subsequent management impact (high and low) was determined by follow-up to assess metabolic response o...

PURPOSE Increased tumor metabolism and hypoxia are related to poor prognosis in solid tumors, including non-small cell lung cancer (NSCLC). PET imaging is a noninvasive technique that is frequently used to visualize and quantify tumor metabolism and hypoxia. The aim of this study was to perform an extensive comparison of tumor metabolism using 2[(18)F]fluoro-2-deoxy-d-glucose (FDG)-PET and hypo...