Abstract Background There are ~3 million transposable elements in the human genome constituting about 42% of all basepairs. Retroelements (REs) ~90% present genome. Active REs considered highly mutagenic and have been implicated multiple steps cancer development progression, as well neurologic diseases. RE activity has functional effects on genome, including maintenance centromere telomere inte...

background and objective: febrile convulsions (fc) are the most common seizure disorders in children. lumbar puncture should be considered in any case with fc who is suspected to intracranial infections. this study determined white blood cell and polymorphonuclear cell counts, protein and glucose levels in cerebrospinal fluids (cfs) of children that were hospitalized with fc. methods: in this c...

background and objectives: febrile convulsion (fc) is the most common seizure disorder in childhood period. some studies have suggested association between seasons and occurrence of fc. this study was designed to determine demographic features, causes and seasonal variations in cases with fc. method: in this descriptive, cross sectional study, 282 children 6- 60 months with fc were admitted to ...

gC(μ) := { F0(C) Fμ(C) if Fμ(C) > 0 ; +∞ if Fμ(C) = 0. Then fC is an upper semicontinuous function: if μ ∈ SM is such that Fμ(C) > 0, then fC is continuous at point μ. Otherwise, fC(μ) = ∞ and fC is trivially upper semicontinuous at point μ. Clearly, one has G(μ) = infC∈C fC(μ) ; as an infimum of upper semicontinuous functions, it is itself upper semicontinuous, and therefore attains its maximu...

Introduction: Noninvasive magnetic resonance imaging (MRI) and targeted drug delivery systems, usually referred to as theranostic agents, are being developed to enable detection, site-specific treatment, and long-term monitoring.   Materials and Methods: To elucidate the effects of coating on cellular uptake and biodistribution of n...

Monocytes and macrophages can take up nonopsonized particles through a direct phagocytic process and IgG-coated particles through combined mechanisms of nonspecific phagocytosis and internalization mediated by specific Fc receptors for IgG (Fc gamma R) on the plasma membrane. In this study, we report the effect of phagocytosis of nonopsonized latex beads on the levels of expression of Fc gamma ...

Macrophage Fc gamma receptors play a significant role in inflammation and host defense. One monocyte/macrophage Fc gamma receptor, Fc gamma RI, the binding site for monomeric IgG, appears to be especially responsive to modulatory signals by hormones and mediators. Since Factor XIIa is generated during inflammation, we studied the effect of XIIa on Fc gamma RI. Factor XIIa, in a concentration-de...

BACKGROUND We aimed to evaluate the role of fecal calprotectin (FC) as a noninvasive marker for the disease activity of ulcerative colitis (UC) in a Korean cohort. METHODS A total of 181 fecal samples were collected from 181 consecutive UC patients between April 2015 and September 2016. FC levels were measured using the Quantum Blue® Calprotectin rapid test. The laboratory test results, parti...

BACKGROUND The relationship between fecal calprotectin (FC) and disease extent in ulcerative colitis (UC) has not been fully elucidated. The aim of this study was to clarify the correlation of FC with disease extent and severity in UC patients. METHODS UC patients scheduled to undergo an ileocolonoscopy were enrolled and fecal samples for FC measurement were collected prior to the procedure. ...

We analyze markers of carnitine insufficiency and deficiency, lysine (LYS) and methionine (MET), in 39 neonates with intrapartum hypoxia (selection criteria: umbilical artery pH <7.20, lactate >1.8 mmol/l and PaO2 <25 mm Hg), and in 35 healthy newborn infants (control group) in the early neonatal period (1-7 days of life). Free (FC), total (TC) carnitine and acylcarnitines (AC=short-chain+long-...