As the hepatic manifestation of the metabolic syndrome, nonalcoholic fatty liver disease (NAFLD) has become the most common cause of asymptomatic liver enzyme elevations in Western nations. Although it is easy to diagnose NAFLD, a liver biopsy is currently required to diagnose nonalcoholic steatohepatitis (NASH). Patients with NASH are those at greatest risk of progression to cirrhosis and, thu...

N 'onalcoholic fatty liver disease (NAFLD) includes a spectrum of hepatic pathology that resembles alcohol-induced liver disease but develops in individuals who are not heavy drinkers. NAFLD is likely to be the most common cause of chronic liver disease in many countries and may also potentiate liver damage induced by other agents, such as alcohol, industrial toxins, and hepatotrophic viruses. ...

Nonalcoholic fatty liver disease (NAFLD) refers to the presence of hepatic steatosis not associated with a significant intake of ethanol. Insulin resistance is central to the pathogenesis of NAFLD; thus obesity, diabetes, and the metabolic syndrome are frequently associated with the disease. Consequently, as these metabolic conditions emerge as major health problems in Western society, it is no...

The early stage liver diseases prediction is an important health related research and using this kind of easily can predict the take remedies. are classified into different types such as cancer, tumor, fatty liver, hepatitis, cirrhosis etc. Non-Alcoholic Fatty Liver Disease a chronic disease which rigorous quite difficult at stages. plays significant role in treating also constraining next cons...

OBJECTIVE Nonalcoholic fatty liver disease is the most common cause of liver dysfunction in Western countries and an independent risk factor for atherosclerotic heart disease. Appropriate noninvasive parameters are lacking for optimal risk stratification of cardiovascular disease in these patients. We evaluated several recently discovered noninvasive parameters for atherosclerosis in patients w...

Non-alcoholic fatty liver disease is one of the most important causes of liver-related morbidity in children. In non-alcoholic fatty liver disease, the activation of liver resident macrophage pool is a central event in the progression of liver injury. The aims of the present study were to evaluate the polarization of liver macrophages and the possible role of Wnt3a production by macrophages in ...

Nonalcoholic fatty liver disease (NAFLD) is characterized by the accumulation of triglycerides in the hepatocytes of patients who don’t abuse alcohol. It ranges in severity from simple steatosis (excessive fat accumulation) to steatohepatitis (liver cell injury and inflammation). Nonalcoholic steatohepatitis (NASH) is a subtype of NAFLD in which steatosis coexists with steatohepatitis. NASH can...

Hepatic steatosis (commonly called fatty liver) is mostly an asymptomatic liver disease, which is diagnosed mostly as a part of an unrelated condition. It was considered to be a benign consequence of chronic alcohol intake. In absence of alcohol intake of >20 g/day, it is termed as nonalcoholic fatty liver disease (NAFLD). Nonalcoholic fatty liver disease consists of accumulation of fat within ...

BACKGROUND Visceral adiposity is the major risk factor for paediatric nonalcoholic fatty liver disease. AIMS Determine the prevalence of nonalcoholic fatty liver disease according to the visceral fat quartile. SUBJECTS 181 obese adolescents including 113 girls (16.58+/-1.56 years) and 68 boys (16.87+/-1.62 years) were evaluated. METHODS The inclusion criteria were obesity and post-puberta...