PURPOSE Evidence suggests that inflammation may drive fatigue in cancer survivors. Research in healthy populations has shown reduced inflammation with higher dietary intake of ω-3 polyunsaturated fatty acids (PUFAs), which could potentially reduce fatigue. This study investigated fatigue, inflammation, and intake of ω-3 and ω-6 PUFAs among breast cancer survivors. METHODS Six hundred thirty-t...

Although it has been indicated that patients with lung cancer experience higher level of fatigue than patients with other cancers, few published studies have focused on the characteristics of this fatigue and how it interferes with daily activities. The purpose of this study was to clarify fatigue prevalence and the factors correlated with fatigue, and to develop a screening method for fatigue ...

PURPOSE Fatigue is a frequent non-motor complaint of patients with Parkinson's disease (PD). Despite increasing knowledge on fatigue, the factors leading to its development are still not recognised. The aim of this investigation was to test, using structural equation modelling, the hypothesis that the influence of disease severity on fatigue is mediated by symptoms of depression in patients wit...

OBJECTIVES To assess the reliability of the Epworth Sleepiness Scale (ESS), Daytime Sleepiness Scale (DSS), Chalder Fatigue Scale (CFS), and Krupp's Fatigue Severity Scale (KFSS) in patients with myotonic dystrophy type 1 (DM1). METHODS In total, 27 patients with DM1 were administered the questionnaires on two occasions, with a 2 week interval. Internal consistency and test retest reliability...

PURPOSE/OBJECTIVES To examine the relationship among sick leave benefits, employment patterns, individual characteristics, and fatigue in patients receiving radiation therapy. DESIGN Prospective, longitudinal design. SETTING A community hospital radiation oncology department. SAMPLE 77 patients receiving radiation therapy to the breast, chest, head and neck, pelvis, or prostate. All were ...

BACKGROUND Single interventions in chronic fatigue syndrome have shown only limited effectiveness, with few studies of comprehensive treatment programmes. AIMS To examine the effect of a comprehensive cognitive-behavioural treatment (CCBT) programme compared with placebo-controlled mirtazapine medication in patients with chronic fatigue, and to study the effect of combined medication and CCBT...

OBJECTIVE To examine the validity and sensitivity to change of the Multiple Sclerosis-Fatigue Self-Efficacy scale. DESIGN A validation study nested within a randomized controlled trial. SETTING Community setting. PARTICIPANTS Adults with a clinically definite diagnosis of multiple sclerosis and significant fatigue taking part in a randomized controlled trial evaluating a group-based fatig...

conclusions orem’s self-care model is significantly effective in reducing the fatigue of multiple sclerosis patients. objectives to determining the effect of orem’s self-care model on fatigue in multiple sclerosis patients. patients and methods this research involved a clinical trial. sixty-three multiple sclerosis patients at the vice-chancellor in treatment affairs of yasuj university of medi...

BACKGROUND AND PURPOSE Poststroke fatigue is common and reduces quality of life. Current evidence for intervention is limited, and this is the first placebo-controlled trial to investigate treatment of poststroke fatigue with the wakefulness promoting drug modafinil. METHODS The trial was randomized, double-blinded, and placebo-controlled. Patients were treated with 400-mg modafinil or placeb...