Human muscle fatigue is considered to be one of the main reasons for Musculoskeletal Disorder (MSD). Recent models have been introduced to define muscle fatigue for static postures. However, the main drawbacks of these models are that the dynamic effect of the human and the external load are not taken into account. In this paper, each human joint is assumed to be controlled by two muscle groups...

I completely concur with Dr Des Spence: Big Pharma is manipulating doctors and exploiting patients, and Big Medicine is neglecting its role to protect patients.1 I can remember, shortly after becoming a GP Principal in 1987, a drug representative trying to persuade us to prescribe evening primrose oil capsules for itching in eczema. The glossy presentation and neurolinguistic programming attemp...

OBJECTIVE There is debate as to the role of inflammatory disease activity in the etiology of rheumatoid arthritis (RA)-related fatigue. We undertook this study to determine the relationship of fatigue to disease activity by examining pathways associated with change in fatigue in subjects starting anti-tumor necrosis factor (anti-TNF) therapy for the first time. METHODS Participants who had be...

Introduction: Until the mechanics of anterior cruciate ligament (ACL) injuries and contributing factors are better elucidated, effective preventive strategies will continue to elude us. Current dogma is that ACL injury results from a single loading cycle, but recent evidence supports tissue fatigue as a possible failure mechanism [1]. In a cadaveric pivot landing model, ACL rupture was found to...