1. Abstract 2. Introduction 2.1. HPV infection and carcinogenesis 2.2. Major transforming activities 2.3. The HPV life cycle 3. Section 3. The HPV E7 protein 3.1. Cellular targets of HPV E7 proteins: the retinoblastoma protein family 3.2. Cellular targets of HPV E7 proteins: cyclin-dependent kinase inhibitors 3.3. Cellular targets of HPV E7 proteins: chromatin modifying factors 4. Section 4. Th...

This paper explores life insurance holdings from a general equilibrium perspective. Drawing on the data explored in Chambers, Schlagenhauf, and Young (2003), we calibrate an overlapping generations lifecycle economy with incomplete asset markets to match facts regarding the uncertainty of income and demographics. We then estimate that life insurance holdings for the purpose of smoothing family ...

(received 2 dec 2012, accepted 31 dec 2012) family photography is a genre of photography which is created in the context of everyday life and includes the photographs that families produce and gather through their lifetime and often keep them in their homes, workplaces and family albums, they documentsome moments in family life. these collections include the photographs which are taken by the p...

This study focuses on the transmission of inequality over the working life. A model of constrained intertemporal choice is used to provide structure to the distributional dynamics of wages, earnings, income and consumption. The mechanisms used to insure labour market shocks are examined in a partial-insurance setting where the manner and scope for insurance depends on the access to credit, the ...

Increasing numbers of adolescents are disclosing their sexual orientation to parents at an earlier stage of the family life cycle than their predecessors. Although we know that parents are coexperiencing the range of difficulties reflected in reports of gay and lesbian youths after disclosure, there is a paucity of investigative research exploring the parents' side of adolescent disclosure. The...

Consumer behaviour analysis represents an important field of study in marketing. Particularly strategy development for marketing and communications will be more focused and effective when marketers have an understanding of the motivations, behaviour and psychology of consumers. While materialism has been found to be one of the important elements in consumer behaviour, compulsive consumption rep...

The Caliciviridae family of small positive sense RNA viruses contains a diverse range of pathogens of both man and animals. The molecular mechanisms of calicivirus genome replication and translation have not been as widely studied as many other RNA viruses. With the relatively recent development of robust cell culture and reverse genetics systems for several members of the Caliciviridae family,...

Background: Polycystic ovary syndrome is the most common disorder in the endocrine system. Hyperandrogenism, hyperinsulinemia, chronic ovulation, and infertility are important Complications of PCOS. Health-related quality-of-life (HRQoL) has a significant reduction in women with polycystic ovary syndrome (PCOS). This reduction can be due to many disorders including: menstrual and sleep disorder...

This paper looks at pathways to reproduction in three pre-transitional societies from a sequence perspective. Rather than studying the final transition in a life course process (i.e. first birth) we compare the full sequence from living in the parental home to having a first birth. Three communities in southern Sweden, eastern Belgium and central Italy are studied using longitudinal individual ...