Hippocampal sclerosis (HS) is the most common pathological substrate for temporal lobe epilepsy with a characteristic pattern of loss of principle neurons primarily in CA1 and hilar subfields. Other cytoarchitectural abnormalities have been identified in human HS specimens, including dispersion of dentate granule cells and cytoskeletal abnormalities in residual hilar cells. The incidence of the...

Amyloid-like inclusions have been associated with Huntington's disease (HD), which is caused by expanded polyglutamine repeats in the Huntingtin protein. HD patients exhibit a high incidence of cardiovascular events, presumably as a result of accumulation of toxic amyloid-like inclusions. We have generated a Drosophila model of cardiac amyloidosis that exhibits accumulation of PolyQ aggregates ...

The covid-19 crisis is global but its socio-economic effects cannot be globally scrutinized. It deeply local and huge. research aimed at finding out assessing community perceptions about Covid-19 in Rwanda. would inspire policymakers to renovate measures policies that help rehabilitating all sectors general more affected groups particular. From 30 districts of Rwanda, 510 respondents have been ...