Plasmodium falciparum being the most lethal plasmodiae is still a major cause of the disease burden and mortality in malaria endemic areas. Due to the wide spread drug resistance in combination with poor socio-economic situation in the vast majority of the endemic countries, malaria is today a great global challenge. The scientific community is, however, progressing. The 23 Mb genome of P. falc...

Chloroquine resistant malaria is a serious problem in Indonesia particularly in Papua. A trial of the existing antimalarial drugs was conducted in Timika, Papua. The objective of the study was to determine the efficacy of cloroquine (CQ) + sulfadoxine-pyrimethamine (SP). Patients with uncomplicated malaria due to Plasmodium falciparum, P. vivax, P. ovale or P. malariae were enrolled and treated...

The Plasmodium falciparum (P. falciparum) (i.e. a protozoan parasite) has been the main cause of malaria which has led to the deaths of many children in sub-Saharan Africa[1,2]. Malaria leads to various abnormalities in children such as renal failure, anaemia and hepatic dysfunction[3,4]. Although several initiatives such as roll back malaria have been introduced by international organizations ...

Malaria is an epidemiological problem at the global level. In Indian sub continent it is a major cause of mortality in immunosupressed patients and in extreme ages of life. Our study is based on early detection of malaria by hematological parameters. A study on 287 malaria patients was carried out at P.D.U Medical College, Rajkot between 1st July 2009 to 31st December 2009 with an objective to ...

Little is known about severe imported Plasmodium falciparum malaria in industrialized countries where the disease is not endemic because most studies have been case reports or have included <200 patients. To identify factors independently associated with the severity of P. falciparum, we conducted a retrospective study using surveillance data obtained from 21,888 P. falciparum patients in Franc...

ABSTRACT To determine the frequency of malaria among children presenting with fever in a flood affected area, and the frequency of Plasmodium vivax and P. falciparum among cases, this cross-sectional study was conducted from 1 September 2010 to 15 January 2011 in the Australian Field Camp and Ehsas Field Hospital, Kot Addu, Muzaffargarh District, Southern Punjab, Pakistan. Each febrile child ag...

Sub-Saharan Africa records each year about thirty-two million pregnant women living in areas of high transmission of Plasmodium falciparum causing malaria. The aim of this study was to carve out the prevalence of asymptomatic malaria among pregnant women and to emphasize its influence on haematological markers. The prevalence of Plasmodium falciparum asymptomatic infection among pregnant women ...

TO THE EDITOR—We thank Cunnington et al [1] for their constructive criticism. They acknowledge that " [n]umerous studies have confirmed the association of parasite sequestration with fatal malaria " but offer an alternate hypothesis, " that extensive sequestration is simply a consequence of endothelial activation and microvascular dysfunction " [1]. However, if sequestration is simply an epiphe...

The Cambodian National Strategic Plan for Elimination of Malaria aims to move step by step toward elimination of malaria across Cambodia with an initial focus on Plasmodium falciparum malaria before achieving elimination of all forms of malaria, including Plasmodium vivax in 2025. The emergence of artemisinin-resistant P. falciparum in western Cambodia over the last decade has drawn global atte...

Background.  African children with severe falciparum malaria commonly have concomitant Gram-negative bacteremia, but co-infection has been thought to be relatively rare in adult malaria. Methods.  Adults with a diagnosis of falciparum malaria hospitalized at 4 tertiary referral hospitals in Myanmar had blood cultures collected at admission. The frequency of concomitant bacteremia and the clinic...