Psoriasis is an autoimmune disease, which symptoms can significantly impair the patient's life quality. It is mainly diagnosed through the visual inspection of the lesion skin by experienced dermatologists. Currently no cure for psoriasis is available due to limited knowledge about its pathogenesis and development mechanisms. Previous studies have profiled hundreds of differentially expressed g...

In this paper, we define a framework for media resources manipulation in an adaptive content delivery system. We discuss the media resources manipulation in an adaptation and negotiation architecture in terms of binary relationship definition using a so-called "related resources" approach, resources extraction, adaptation and delivery. We show how different resources can be related by predefine...

—Many aspects of small-scale fisheries hinder our efforts to understand their dynamics, as required for sustainable management. For example, there is no widely accepted definition of small-scale fisheries or global data on number of small-scale fishers and their catches. One reason for this is that most research on small-scale fisheries is done at community level and tends to focus on immediate...

As Web services become more and more popular, how to manage multimedia Web services that can be composed as value-added service solutions remains challenging. This paper presents a service-oriented multimedia componentization model to support Quality of Service (QoS)centered, device-independent multimedia Web services, which seamlessly incorporates cuttingedge technologies relating to Web servi...

Automatic capture of the user’s interaction environment for useradapted interaction and evaluation purposes is an unexplored area in the Web Accessibility research field. This paper presents an application that collects user data regarding assistive technologies (be either software or hardware) in an unobtrusive way. As a result, CC/PP based profiles are created so that interoperability between...

In many manufacturing processes, the quality of a product is characterized by a non-linear relationship between a dependent variable and one or more independent variables. Using nonlinear regression for monitoring nonlinear profiles have been proposed in the literature of profile monitoring which is faced with two problems 1) the distribution of regression coefficients in small samples is unkno...

background: dyslipidemia is considered an independent risk factor for coronary heart disease (chd). in the present study, we examined lipid profiles and paraoxonase 1 (pon1) activity and atherogenic indexes status and the relationship of pon1 activity by high-density lipoprotein (hdl) and atherogenic indexes in chd patients and healthy people. methods: the aim of the study was to compare pon1, ...

BACKGROUND Chromatin immunoprecipitation combined with genome tile path microarrays or deep sequencing can be used to study genome-wide epigenetic profiles and the transcription factor binding repertoire. Although well studied in a variety of cell lines, these genome-wide profiles have so far been little explored in vertebrate embryos. PRINCIPAL FINDINGS Here we report on two genome tile path...

The analysis of regulatory regions in genome sequences is strongly based on the detection of potential transcription factor binding sites. The preferred models for representation of transcription factor binding specificity have been termed position-specific scoring matrices. JASPAR is an open-access database of annotated, high-quality, matrix-based transcription factor binding site profiles for...