Today, one of the major challenges in biophysics is to disclose the molecular mechanisms underlying biological processes. In such a frame, the understanding of the survival strategies in extreme conditions received a lot of attention both from the scientific and applicative points of view. Since nature provides precious suggestions to be applied for improving the quality of life, extremophiles ...

There are several pieces of evidence showing occurrence of pulmonary edema (PE) in healthy subjects in extreme conditions consisting of extreme psychophysical demand in normal environment and psychophysical performances in extreme environment. A combination of different mechanisms, such as mechanical, hemodynamic, biochemical, and hypoxemic ones, may underlie PE leading to an increase in lung v...

Modeling non-adiabatic phenomena and materials at extremes has been a long-standing challenge for computational chemistry and materials science, particularly for systems that undergo irreversible phase transformations due to significant electronic excitations. Ab initio and existing quantummechanics approximations to the Schrödinger equation have been limited to ground-state descriptions or few...

System Metaphor is one of the key practices of Extreme Programming (XP). Unfortunately, the System Metaphor practice is poorly understood, and is the practice XP teams most commonly choose to ignore. In this paper, we provide a small collection of patterns that teams can use to develop metaphors for their systems, and for evaluating system metaphors. We hope these patterns will encourage Extrem...

Krein [1] mentioned that for each PD equation we have two extreme operators, one is the minimal in which solution and its derivatives on the boundary are zero, the other one is the maximal operator in which there is no prescribed boundary conditions. They claim it is not possible to have a related boundary value problem for an arbitrarily chosen operator in between. They have only considered lo...

We give the necessary conditions of extreme points and strongly extreme points in the unit ball of Köthe–Bochner spaces. The conditions have been shown to be sufficient earlier.