' 2004 Canadian Medical Association H has been described as a paraneoplastic syndrome associated with most malignant lesions but is very rarely reported in association with germ cell tumours. Paraneoplastic hypercalcemia is typically related to the production of parathyroid hormone–related peptide (PTHrP). I describe here what I believe to be the first case of germ cell tumour with hypercalcemi...

The distribution and behavior of chick primordial germ cells (PGC) injected into quail embryos were examined. PGC from chick embryos at stages 13-14 were injected into the blood stream of quail embryos at stages 15-20. After one day, the quail embryos were examined histologically. The chick PGC in the quail embryos could be readily identified by the histochemical PAS technique, whereas quail PG...

Introduction: Retroperitoneum is the third most common extragonadal site for occurrence of teratoma in children, after sacrococcygeal region and gonadal sites. Although many authors have previously reported laparoscopic removal of benign retroperitoneal teratoma in adults, the experience in pediatric setting is extremely limited. Material and methods: We report our experience with laparoscopic ...

Teratomas comprise the most common extragonadal germ cell tumors in childhood. Most teratomas involving the thyroid are benign and occur in children. However, the adult cases reported are mostly malignant and commonly arise in the thyroid. We report a case of a 31-yr-old female with a huge neck mass. Pathologic examination revealed it to be malignant teratoma composed of primitive neuroepitheli...

A 3-year-old female neutered Staffordshire Bull Terrier presented with a mixed germ cell tumor involving the base of the iris and the ciliary body of the right eye. The tumor mass was composed primarily of packeted vacuolated, polygonal (hepatoid) cells and small round cells; epithelial cells lining tubuloacinar structures were a less prominent component. The hepatoid and round cells stained po...