Objective(s) A sensitive liquid chromatographic method for the analysis of clarithromycin- a macrolide antibiotic- in human serum, using pre-column derivatization with 9-fluorenylmethyl chloroformate (FMOC-Cl) is described. Materials and Methods The method involved liquid-liquid extraction of the drug and an internal standard (amantadine) followed by pre-column derivatization of the analytes...

In most cases isolation of drugs from biological samples taken from drug overdose cases has been performed by solvent extraction, for example at pH 9.5 (1), pH 7 (2), or without pH adjustments (3). These techniques do not efficiently extract both strong bases (such as amphetamine) and strong acids (such as acetylsalicylic acid). A two-step extraction of the biological sample at different pH val...

in the present investigation the biosorption potential of rosa gruss an teplitz (red rose) waste biomass (rrwb) for the removal of pb(ii) and co(ii) from aqueous solutions was studied. the effect of different process parameters such as ph, biosorbent dose, biosorbent size, temperature, contact time, initial metal concentration and pretreatments on the biosorption capacity of this waste biomass ...