Controlling cell proliferation is one of the hallmarks of cancer. A number of critical checkpoints ascertain progression through the different stages of the cell cycle, which can be aborted when perturbed, for instance by errors in DNA replication and repair. These molecular checkpoints are regulated by a number of proteins that need to be present at the right time and quantity. The ubiquitin s...

One of the most popular utilization of expert systems is supporting credit granting decisions. Usually, certain systems without possibilities of representing of uncertain knowledge are used. The main aim of this paper is to compare certain and uncertain expert systems supporting credit granting decisions, and stating which one is superior over another.

One of the most popular utilization of expert systems is supporting credit granting decisions. Usually, certain systems without possibilities of representing of uncertain knowledge are used. The main aim of this paper is to compare certain and uncertain expert systems supporting credit granting decisions, and stating which one is superior over another.

Four new associate editors have been appointed to join Dr Elif Ubeyli, who will also continue in this role. They have been selected based on their research expertise, their past experience with Expert Systems and their dedication as reviewers and guest editors since I have been EiC. You can read a little of what they say about themselves in the biographies included at the end of this announceme...

In this paper, we present a method for conceptual modelling of a real-time expert system for monitoring and control. Five models of interface model, object model, task model, inference model and strategy model, are generated by using this method to describe diierent aspects of the system. We illustrate the ve models by giving examples from modelling an expert system for monitoring and control o...

The performance of a case-based diagnosis system should be validated before it can be applied in a critical operational environment. This paper proposes a framework for a validation process of case-based diagnosis systems. This framework is developed from existing work on expert system validation and on evaluation and improvement of the performance of casebased reasoning systems. First results ...

One of the most popular utilization of expert systems is supporting credit granting decisions. Usually, certain systems without possibilities of representing of uncertain knowledge are used. The main aim of this paper is to compare certain and uncertain expert systems supporting credit granting decisions, and stating which one is superior over another.

In this paper, all of the potential synthesis cases in distributed expert systems (DESs) are identiied based on the relationship between the original evidence sets of solutions, and the types of DESs are classiied based on the relationship of knowledge and available data of expert systems. The innovative ideas are that the relationships among the synthesis cases and the types of DESs are recogn...