Cladribine acts as an antineoplastic, immunosuppressive and anti-inflammatory agent. The aim of this study was to examine the possible impact of this drug on the epidermis of Wistar rats. The control group received standard feed and water. The experimental group I was treated with cladribine in a schema corresponding to the treatment of multiple sclerosis in humans. The material for microscopic...

Background and Methodology: Gentamicin is a broad-spectrum antibiotic with restricted application in man and stock due to its side effects such as Nephrotoxicity and autotoxicity. Cinnamon bark has antioxidant properties. This is the first study on the protective effects of the hydroalcoholic extract of cinnamon on gentamicin-induced nephrotoxicity.Methods and Materials: Thirty-six mature femal...

Background: To promote general health in patients with hepatitis, it is vital to develop effective interventions to improve the lifestyle of these patients. The present study aimed to investigate the effectiveness of group cognitive-behavioral therapy (CBT) on the lifestyle of patients with hepatitis B. Methods: This was a quasi-experimental study with pretest-posttest control group design. A ...

To determine whether the traditional Chinese herbal formula of Shen Ling Baizhu (SLB) could modulate the composition of the gut microbiota and alleviate diarrhoea in suckling piglets, twenty-four newly born piglets (Large White × Landrace × Duroc) were selected and allocated to 4 groups (control group and experimental groups I, II, and III) randomly. Faecal microbiome composition was assessed b...

aim and background: emotion focused couple therapy is one of the methods that has focused on the negative cycles of interaction caused from deep emotional vulnerability. the purpose of this study was to determine the effect of emotionally focused couple therapy on reducing the damage caused by marital infidelity. methods and materials: the statistical sample included 30 couples that were select...

To evaluate the prognostic significance of clinicopathological measurement in the diagnosis of acute myocardial infarction (MI) in sheep, acute MI was induced by ligation of left anterior descending coronary artery (LAD). For this purpose, twenty four healthy sheep were divided into the sham-operated or control group (group I, thoracotomy without MI) and the experimental group (group II, with M...

There have been many attempts for regeneration of peripheral nerve injury. In this study, we examined the in vivo effects of non-differentiated and neuronal differentiated adipose-derived stem cells (ADSCs) in inducing the neuronal regeneration in the Sprague-Dawley (SD) rats undergoing nerve defect bridged with the PCL nanotubes. Then, we performed immunohistochemical and histopathologic exami...

objective: medicinal plants are widely used throughout the world. since these plants are known to have minimal side effects, many people embrace them. the golpar plant, scientifically known as heracleum persicum (h. persicum), is a common asian and iranian medicinal plant. the use of golpar is recommended in traditional medicine as a contraceptive medication for females; however, no scientifica...

background & aim: considering that antioxidants are known as effective free radicals scavenger, it may be able to improve the in vitro oocyte maturation and the fetal quality. this study was designed to determine the effect of gundelia tournefortii leaves (gte) hydro-alcoholic extract as a source of antioxidant on in vitro oocyte maturation. experimental: germinal vasicle (gv) were recovere...