نتایج جستجو برای: exact dynamic stiffness matrix
تعداد نتایج: 900433 فیلتر نتایج به سال:
In traditional finite element based modal analysis of linear non-conservative structures, the modal shapes are determined solely based on stiffness and mass. Damping effects are included by implicitly assuming that the damping matrix can be diagonalized by the undamped modes. The approach gives real valued mode shapes and modal coordinates. While this framework is suitable for analysis of most ...
This paper presents the stiffness characteristics of a three-prismatic-universal–universal (3-PUU) translational parallel kinematic machine (PKM). The stiffness matrix is derived intuitively based upon an alternative approach considering actuations and constraints, and the compliances subject to both actuators and legs are involved in the stiffness model. The stiffness performance of the manipu...
KEY POINTS This paper describes a novel model that allows exploration of matrix-induced cardiomyocyte adaptations independent of the passive effect of matrix rigidity on cardiomyocyte function. Detachment of adult cardiomyocytes from the matrix enables the study of matrix effects on cell shortening, Ca2+ handling and myofilament function. Cell shortening and Ca2+ handling are altered in cardiom...
Matrix stiffening is a prominent feature of pulmonary fibrosis. In this study, we demonstrate that matrix stiffness regulates the ability of fibrotic lung myofibroblasts to invade the basement membrane (BM). We identify α6-integrin as a mechanosensing integrin subunit that mediates matrix stiffness-regulated myofibroblast invasion. Increasing α6-expression, specifically the B isoform (α6B), cou...
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