Epistaxis occurs in approximately 60% of the general population. Every tenthperson requires treatment a hospital setting. all age groups,reaching its peak children around 10 years and adults 80years age. The frequency intensity epistaxis are anatomically based onnumerous vascular connections. cause most cases can bedetermined on basis detailed history physical examination. Thereare number treat...

Recent evidence on the genomic integrity of non-malignant cells surrounding carcinoma cells has reinvigorated the discussion about the origin of the altered phenotype exhibited by carcinoma associated fibroblasts. Many hypotheses have been proposed for the origin of these altered cells, including standard connective tissue acute phase and stress response, fibroblast senescence, reciprocal inter...

There is growing scientific evidence linking excess body weight to breast cancer risk. However, there is no common consensus on this relation due partly to methodologies used, populations studied and the cancer subtype. We report here a summary of the present state of knowledge on the role of overweight and obesity in pathogenesis of breast cancer and possible mechanisms through which excess bo...

Delhi reports highest magnitude of risks for males and Chennai for females in all cancers combined during childhood period. Significant increase in trends of childhood cancer risk detected for all sites combined in Chennai for males and in Mumbai for females. The trends observed may likely to give an insight into further understanding of childhood cancer etiology. L Satyanarayana, Smita Asthana...

To explore breast cancer etiology, literature was searched using Medline. We explored the 1) plausibility of smoking in breast carcinogenesis; 2) physiological properties, susceptibility windows, and exposure timing of breast cells; 3) role of exogenous hormones in breast carcinogenesis; 4) biological mechanism of synergistic interactions between smoking and exogenous hormones in breast carcino...