Growth in world population will inevitably leads to increased demand for protein for humans and animals. Protein from insects and blood plasma are being considered as possible alternatives, but more research on their nutritional quality and health effects is needed. Here, we studied the effect of dietary protein source on metabolism and metabolic amine profiles in serum and urine of mice. Group...

BACKGROUND The advancement of gene silencing via RNA interference is limited by the lack of effective short interfering RNA (siRNA) delivery vectors. Rational design of polymeric carriers has been complicated by the fact that most chemical modifications affect multiple aspects of the delivery process. In this work, the extent of primary amine acetylation of generation 5 poly(amidoamine) (PAMAM)...

beta H-crystallin was exposed to radiolytically generated hydroxyl radicals at defined radical concentrations, and its capacity to act as an amine-acceptor substrate and as an amine-donor substrate for transglutaminase were investigated. [14C]Methylamine was used as a probe for labelling amine-acceptor sites; a novel biotinylated hexapeptide was used to label amine-donor sites. The results demo...

Monoamine oxidase (MAO) enzymes regulate the level of neurotransmitters by catalyzing the oxidation of various amine neurotransmitters, such as serotonin, dopamine and norepinephrine. Therefore, they are the important targets for drugs used in the treatment of depression, Parkinson, Alzeimer and other neurodegenerative disorders. Elucidation of MAO-catalyzed amine oxidation will provide new ins...

The aging of triazine amine in soil was studied during a time course of 119 d by measuring bioavailability in terms of mineralization after inoculation of the triazine amine-degrading bacterium Rhodococcus erythropolis TA57. The bioavailability was measured in four soil samples: A-, B-, and C-horizons from an agricultural soil profile and in a peat soil. The sorption of triazine amine in the so...

A family of iron(II) carbonyl hydride complexes supported by either a bifunctional PNP ligand containing a secondary amine, or a PNP ligand with a tertiary amine that prevents metal–ligand cooperativity, were found to promote the catalytic hydrogenation of CO2 to formate in the presence of Brønsted base. In both cases a remarkable enhancement in catalytic activity was observed upon the addition...

Oxidation of the biologically important polyamines spermine and spermidine by plasma amine oxidase (PAO) was specified many years ago to occur at the terminal primary rather than internal secondary amine positions. However, the finding of sequential enzymatic conversion of spermine to spermidine and then to putrescine (1, 4-butanediamine) is superficially suggestive of metabolism at the seconda...

BACKGROUND Methamphetamine is a major drug of abuse with no effective pharmacotherapy available. Trace amine associated receptor 1 is implicated in cocaine addiction and represents a potential therapeutic target. However, the effects of trace amine associated receptor 1 agonists on addiction-related behavioral effects of methamphetamine are unknown. METHODS This study examined the effects of ...

Soda lignin was divided into two fractions with different molecular weights by methanol extraction. Lignin amine was synthesized from the low-molecular-weight lignin fraction via Mannich reaction and was used for interfacial modification of poly-(vinylchloride) (PVC)/wood-flour composites. The PVC/wood-flour composites were prepared from surface-treated wood flour and PVC by melt compounding. T...

A stimuli-responsive hexameric oligophenol host undergoes amine-induced co-operative folding from a more fluorescent, more linear structure into less fluorescent, more curved or helically folded states, enabling easy identification and classification of the bound amine guests.