نتایج جستجو برای: esr2 gene
تعداد نتایج: 1141525 فیلتر نتایج به سال:
Biliary tract cancer encompasses tumors of the gallbladder, bile duct and ampulla of Vater. Gallbladder cancer is more common in women, whereas bile duct cancer is more common in men, suggesting that sex hormones may play a role in the etiology of these cancers. The intracellular action of estrogens is regulated by the estrogen receptor (ESR); thus, we examined the role of common genetic varian...
تنش دمای پایین یکی از مهم ترین عوامل محیطی است که عملکرد گیاهان را محدود می نماید. شبکه وسیعی از ژن های مختلف در تنظیم تحمل گیاه به این تنش نقش ایفا می نمایند. در این تحقیق، نخست 921 عدد از ژن های مذکور از تحقیقات و مقالات معتبر علمی استخراج گردید و سپس به منظور شناسایی ژن های مشابه با آنها در ژنوم کامل دو گیاه سیب (malus domestica)و انگور (vitis vinifera)، توالی آمینو اسیدی این ژن ها در گیاه م...
Breast cancer is the most common female malignancy in the Western world and approximately 5-10% of all breast cancer cases present with some degree of family history. In the mid-nineties genetic linkage analyses successfully identified two breast cancer predisposing genes, BRCA1 and BRCA2. Mutations in these genes are responsible for the majority of large early onset breast and breast-ovarian c...
UNLABELLED The presence of estrogen receptor (ER) in breast cancer is a prognostic indicator for both disease-free and overall survival. 16α-(18)F-fluoro-17β-estradiol ((18)F-FES) with PET is a noninvasive test for evaluation of ER expression and has been used for predicting response to endocrine therapy in patients with ER-positive metastatic breast cancer. The purpose of this study was to cor...
Daily Rhythms in Expression of Genes of Hepatic Lipid Metabolism in Atlantic Salmon (Salmo salar L.)
In mammals, several genes involved in liver lipid and cholesterol homeostasis are rhythmically expressed with expression shown to be regulated by clock genes via Rev-erb 1α. In order to elucidate clock gene regulation of genes involved in lipid metabolism in Atlantic salmon (Salmo salar L.), the orphan nuclear receptor Rev-erb 1α was cloned and 24 h expression of clock genes, transcription fact...
We integrate systemic financial instability in an empirical macroeconomic model for the euro area. We find that at times of widespread financial instability the macroeconomy functions fundamentally differently from tranquil times. We employ a richly specified MarkovSwitching Vector Autoregression model to capture the dynamic relationships between a set of core macroeconomic variables and a nove...
mAbs capable of disabling heterodimeric kinase complexes of the epidermal growth factor receptor (EGFR) and human EGFR type 2/neu have therapeutic relevance to various human cancers. In this study, we demonstrate that in addition to the dimer, EGFR and human EGFR type 2 can associate as homo- and heterotetramers. EGF-induced phosphorylation of the tetramers was significantly lower than that of ...
The association of ovarian carcinoma risk with the polymorphism rs1271572 in the estrogen receptor beta (ESR2) gene was examined in 4946 women with primary invasive ovarian carcinoma and 6582 controls in a pooled analysis of ten case-control studies within the Ovarian Cancer Association Consortium (OCAC). All participants were non-Hispanic white women. Odds ratios (ORs) and 95% confidence inter...
Chlordecone (CD), also known as Kepone, is an organochlorine insecticide that has been used in banana crops the French West Indies. Due to long-term contamination of soils and water, population still exposed CD. Exposure CD adulthood associated with increased risk prostate cancer (PCa). We examined transgenerational effects on murine tissue. pregnant Swiss mice The prostates from directly (F1) ...
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